Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 15/20 | 0.36 |
| ▸ | SLC16A1 | P53985 | 14/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3694441 | 0.90 | SLC16A3 (0.40) | SLC16A3SLC16A1PDE4BHTR2CSLC6A4 | |
| SCHEMBL3701337 | 0.86 | SLC16A3 (0.36) | SLC16A3SLC16A1PDE4BHTR2CSLC6A4 | |
| SCHEMBL3698141 | 0.85 | SLC16A3 (0.37) | SLC16A3SLC16A1PDE4BMEN1KMT2A | |
| SCHEMBL3692824 | 0.82 | SLC16A3 (0.36) | SLC16A3SLC16A1PDE4BHTR2CSLC6A4 | |
| SCHEMBL3706235 | 0.82 | HTR2C (0.49) | SLC16A3SLC16A1HTR2CSLC6A4 | |
| SCHEMBL3029606 | 0.81 | SLC16A3 (0.38) | SLC16A3SLC16A1PDE4BMEN1KMT2A | |
| SCHEMBL3701902 | 0.81 | SLC16A3 (0.38) | SLC16A3SLC16A1PDE4BMEN1KMT2A | |
| SCHEMBL3701987 | 0.81 | SLC16A3 (0.36) | SLC16A3SLC16A1PDE4BP2RY1MEN1 | |
| SCHEMBL3701339 | 0.79 | LMNA (0.36) | SLC16A3SLC16A1PDE4BMEN1KMT2A | |
| SCHEMBL4201749 | 0.79 | SLC16A3 (0.36) | SLC16A3SLC16A1PDE4BP2RY1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009041705-A9 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2009-08-13 | — | — | WO | disclosed |