Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 10/20 | 0.37 |
| ▸ | SLC16A1 | P53985 | 9/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.32 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3702435 | 0.92 | RIPK1 (0.36) | SLC16A3SLC16A1GPR132 | |
| SCHEMBL3690715 | 0.90 | FPR1 (0.33) | MAPTKMT2AALDH1A1CNR1 | |
| SCHEMBL3697750 | 0.88 | TSHR (0.32) | MEN1KMT2ALMNA | |
| SCHEMBL3029599 | 0.88 | SLC16A3 (0.37) | SLC16A3SLC16A1MAPTMEN1KMT2A | |
| SCHEMBL3692822 | 0.86 | SLC16A3 (0.35) | SLC16A3SLC16A1MAPTMEN1KMT2A | |
| SCHEMBL3706679 | 0.84 | FPR1 (0.33) | — | |
| SCHEMBL3698138 | 0.83 | SLC16A3 (0.38) | SLC16A3SLC16A1MAPTMEN1KMT2A | |
| SCHEMBL3700573 | 0.83 | SLC16A3 (0.39) | SLC16A3SLC16A1ALDH1A1CNR1 | |
| SCHEMBL3700852 | 0.82 | FPR1 (0.36) | — | |
| SCHEMBL4201749 | 0.82 | SLC16A3 (0.36) | SLC16A3SLC16A1MEN1KMT2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190822-A2 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009041705-A9 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2009-08-13 | — | — | WO | disclosed |
| WO-2009041705-A2 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-02 | — | — | WO | disclosed |