SCHEMBL4201855

SCHEMBL4201855

CC(C)NC(=S)Nc1ccccc1CNC(C)CC1CCCCC1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.42
HPGD P15428 1/20 0.42
ALDH1A1 P00352 4/20 0.40
LMNA P02545 4/20 0.40
HTT P42858 2/20 0.40
ALOX12 P18054 1/20 0.40
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
MAPT P10636 2/20 0.36
GAA P10253 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4184212 1.00 SMN1; SMN2 (0.42) SMN1; SMN2HPGDALDH1A1LMNAHTT
SCHEMBL4204380 0.87 SMN1; SMN2 (0.39) SMN1; SMN2HPGDALDH1A1LMNAHTT
SCHEMBL4197445 0.86 KMT2A (0.48) SMN1; SMN2ALDH1A1HTTKMT2AMEN1
SCHEMBL4196629 0.86 KMT2A (0.48) SMN1; SMN2ALDH1A1HTTKMT2AMEN1
SCHEMBL4195095 0.86 KMT2A (0.48) SMN1; SMN2ALDH1A1HTTKMT2AMEN1
SCHEMBL4192672 0.86 KMT2A (0.52) SMN1; SMN2ALDH1A1KMT2AMEN1GAA
SCHEMBL4192548 0.83 KMT2A (0.47) SMN1; SMN2HPGDALDH1A1KMT2AMEN1
SCHEMBL4195568 0.82 METAP2 (0.40) SMN1; SMN2HPGDALDH1A1KMT2AMEN1
SCHEMBL4196854 0.80 KMT2A (0.42) KMT2AMEN1NPSR1L3MBTL1
SCHEMBL4196799 0.80 CCR3 (0.50) SMN1; SMN2ALDH1A1HTTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP claimed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US claimed
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP disclosed
US-8076370-B2 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2011-12-13 US disclosed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215764-A1 Antimicrobial agents TUFM, RPS17, HARS1 SMN1; SMN2 3369/4885HPGD 2593/4885ALDH1A1 2744/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.