SCHEMBL4196854

SCHEMBL4196854

CC(CC1CCCCC1)NCc1ccccc1NC(=O)NC(=S)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.42
PPM1D O15297 1/20 0.41
CTSL P07711 1/20 0.39
CTSB P07858 1/20 0.39
CTSS P25774 1/20 0.39
CTSK P43235 1/20 0.39
USP30 Q70CQ3 2/20 0.39
CCR3 P51677 6/20 0.39
NPY5R Q15761 1/20 0.37
MEN1 O00255 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
F2RL1 P55085 1/20 0.36
CTSD P07339 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4197653 0.90 CTSL (0.45) KMT2APPM1DCTSLCTSBCTSS
SCHEMBL4196799 0.84 CCR3 (0.50) KMT2ACCR3NPY5RMEN1
SCHEMBL4196629 0.84 KMT2A (0.48) KMT2APPM1DCTSLCTSBCTSS
SCHEMBL4195095 0.84 KMT2A (0.48) KMT2APPM1DCTSLCTSBCTSS
SCHEMBL4197445 0.84 KMT2A (0.48) KMT2APPM1DCTSLCTSBCTSS
SCHEMBL4192548 0.84 KMT2A (0.47) KMT2APPM1DNPY5RMEN1NPSR1
SCHEMBL4202574 0.80 RAB9A (0.46) KMT2ACCR3NPY5RMEN1TDP1
SCHEMBL4201855 0.80 SMN1; SMN2 (0.42) KMT2AMEN1NPSR1L3MBTL1
SCHEMBL4184212 0.80 SMN1; SMN2 (0.42) KMT2AMEN1NPSR1L3MBTL1
SCHEMBL4196843 0.80 EPHX1 (0.52) KMT2AMEN1NPSR1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP claimed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US claimed
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP disclosed
US-8076370-B2 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2011-12-13 US disclosed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US disclosed
EP-1879877-A2 ANTIMICROBIAL AGENTS Ranbaxy Laboratories Limited (IN) 2008-01-23 EP disclosed
WO-2006117762-A2 ANTIMICROBIAL AGENTS RANBAXY LABORATORIES LIMITED (IN) 2006-11-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215764-A1 Antimicrobial agents TUFM, RPS17, HARS1 KMT2A 2047/4885PPM1D 3098/4885CTSL 1074/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.