SCHEMBL4190895

SCHEMBL4190895

COc1cccc(OCCCOC(=O)C(C)=COc2ccc3ccccc3c2)c1OCCCOC(=O)C(C)=COc1ccc2ccccc2c1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.44
KMT2A Q03164 6/20 0.44
LMNA P02545 4/20 0.44
SMN1; SMN2 Q16637 4/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
MAPT P10636 4/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
HPGD P15428 4/20 0.41
MAPK1 P28482 2/20 0.41
ATM Q13315 1/20 0.39
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4204704 0.89 KDM4E (0.40) MEN1KMT2ALMNASMN1; SMN2RAB9A
SCHEMBL4196022 0.86 KDM4E (0.38) MEN1KMT2ALMNARAB9AMAPT
SCHEMBL4193372 0.85 PPARA (0.46) SMN1; SMN2NPC1RAB9AMAPTMAPK1
SCHEMBL4190462 0.84 KDM4E (0.44) MEN1KMT2ASMN1; SMN2NPC1RAB9A
SCHEMBL4198605 0.82 KDM4E (0.36) MEN1KMT2ARAB9AALDH1A1KDM4E
SCHEMBL4198178 0.82 FFAR4 (0.42) MEN1KMT2ALMNASMN1; SMN2MAPT
SCHEMBL4198432 0.82 PPARA (0.43) ALDH1A1KDM4E
SCHEMBL4194269 0.77 ALDH1A1 (0.40) MEN1KMT2AL3MBTL1HPGDMAPK1
SCHEMBL4197471 0.76 PPARG (0.41) MAPTL3MBTL1
SCHEMBL4198157 0.76 FFAR4 (0.41) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1627867-B1 (METH)ACRYLIC ESTER COMPOUND AND USE THEREOF MITSUI CHEMICALS INC (JP) 2016-01-20 EP disclosed
US-7534909-B2 (Meth) acrylic ester compound and use thereof MITSUI CHEMICALS, INC. (JP) 2009-05-19 US disclosed
US-20070078198-A1 (Meth) acrylic ester compound and use thereof MITSUI CHEMICALS, INC. (JP) 2007-04-05 US disclosed
EP-1627867-A1 (METH)ACRYLIC ESTER COMPOUND AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2006-02-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070078198-A1 (Meth) acrylic ester compound and use thereof METTL14, PAM, TAS2R41 MEN1 744/4885KMT2A 266/4885LMNA 4549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.