SCHEMBL4205681

SCHEMBL4205681

CCO[SiH](NC1CCCCC1C)OCC

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 7/20 0.35
TAS1R1 Q7RTX1 7/20 0.35
EPHX1 P07099 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
POLB P06746 1/20 0.33
USP2 O75604 1/20 0.33
TAS1R2 Q8TE23 4/20 0.32
TSHR P16473 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3886589 0.74 THRB (0.36) EPHX1KDM4EALDH1A1
SCHEMBL10069387 0.66 FUCA1 (0.43) TAS1R3TAS1R1EPHX1SMN1; SMN2POLB
SCHEMBL10151647 0.66 FUCA1 (0.43) TAS1R3TAS1R1EPHX1SMN1; SMN2POLB
SCHEMBL10293237 0.66 FUCA1 (0.43) TAS1R3TAS1R1EPHX1SMN1; SMN2POLB
SCHEMBL10151965 0.66 FUCA1 (0.43) TAS1R3TAS1R1EPHX1SMN1; SMN2POLB
SCHEMBL4210283 0.65 TAS1R3 (0.35) TAS1R3TAS1R1EPHX1SMN1; SMN2POLB
SCHEMBL21232876 0.64 EPHX1 (0.42) TAS1R3TAS1R1EPHX1SMN1; SMN2POLB
SCHEMBL19817617 0.64 EPHX1 (0.42) TAS1R3TAS1R1EPHX1SMN1; SMN2POLB
SCHEMBL5148530 0.64 TAS1R3 (0.35) TAS1R3TAS1R1EPHX1SMN1; SMN2POLB
SCHEMBL9396676 0.64 EPHX1 (0.45) TAS1R3TAS1R1EPHX1SMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090253873-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING POLYMER OR COPOLYMER OF OLEFIN USING THE SAME TOHO CATALYST CO., LTD (JP) 2009-10-08 US disclosed