SCHEMBL3886589

SCHEMBL3886589

CCO[SiH](NC1CCCCC1)OCC

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ALDH1A1 P00352 4/20 0.35
HSD17B10 Q99714 1/20 0.35
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
NPSR1 Q6W5P4 2/20 0.33
SHBG P04278 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
EPHX1 P07099 1/20 0.32
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3887622 0.75 ALDH1A1 (0.39) ALDH1A1HSD17B10NPSR1GAAMEN1
SCHEMBL4205681 0.74 TAS1R3 (0.35) ALDH1A1EPHX1KDM4E
SCHEMBL141766 0.72 THRB (0.35) THRBATML3MBTL1ALDH1A1HSD17B10
SCHEMBL146575 0.71 KDM4E (0.36) THRBATML3MBTL1ALDH1A1HSD17B10
SCHEMBL4449826 0.71 THRB (0.34) THRBATML3MBTL1ALDH1A1HSD17B10
SCHEMBL1516288 0.71 THRB (0.34) THRBATML3MBTL1ALDH1A1HSD17B10
SCHEMBL198501 0.70 ALDH1A1 (0.50) ALDH1A1HSD17B10LMNAGAANPC1
SCHEMBL20985091 0.70 THRB (0.33) THRBATML3MBTL1ALDH1A1MMP1
SCHEMBL21874986 0.69 THRB (0.33) THRBATML3MBTL1ALDH1A1HSD17B10
SCHEMBL125661 0.68 KDM4E (0.41) THRBATML3MBTL1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7572303-B2 A symmetrical dialkyl carbonate, a metal, borong, silicon, or group 7 compound, a hydrogen or hydrocarbon-based fuel, an oxidizer, and a metallic cocatalyst; minimized hydrolysis; improved combustion and storage stability OCTANE INTERNATIONAL, LTD. (US) 2009-08-11 US disclosed
EP-0954558-B1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 2006-06-14 EP disclosed
US-20050044778-A1 Fuel compositions employing catalyst combustion structure OCTANE INTERNATIONAL, LTD. 2005-03-03 US disclosed
US-20040237384-A1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2004-12-02 US disclosed
US-6652608-B1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2003-11-25 US disclosed
CN-1125074-C Preparation of alkyl (amino) dialkoxysilanes SIVENTO INC (US) 2003-10-22 CN disclosed
CN-1292794-A Preparation of alkyl (amino) dialkoxysilanes SIVENTO INC (US) 2001-04-25 CN disclosed
EP-1051461-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR, William C. (US) 2000-11-15 EP disclosed
WO-1999066009-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR WILLIAM C (US) 1999-12-23 WO disclosed
EP-0954558-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR, William C. (US) 1999-11-10 EP disclosed
WO-1998026028-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 1998-06-18 WO disclosed