Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 12/20 | 0.62 |
| ▸ | MEN1 | O00255 | 10/20 | 0.62 |
| ▸ | AMY1A | P0DUB6 | 5/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.51 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.49 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11045187 | 0.87 | KMT2A (0.81) | KMT2AMEN1AMY1AL3MBTL1POLB | |
| SCHEMBL6654187 | 0.81 | PTGS2 (0.68) | KMT2AMEN1AMY1AL3MBTL1POLB | |
| SCHEMBL6654185 | 0.81 | PTGS2 (0.68) | KMT2AMEN1AMY1AL3MBTL1POLB | |
| SCHEMBL420585 | 0.79 | KMT2A (0.72) | KMT2AMEN1AMY1AL3MBTL1POLB | |
| SCHEMBL12900139 | 0.75 | DYRK1A (0.46) | KMT2AMEN1POLBALDH1A1MAPT | |
| SCHEMBL446375 | 0.75 | DYRK1A (0.46) | KMT2AMEN1POLBALDH1A1MAPT | |
| SCHEMBL446376 | 0.75 | DYRK1A (0.46) | KMT2AMEN1POLBALDH1A1MAPT | |
| SCHEMBL3887396 | 0.74 | KMT2A (0.60) | KMT2AMEN1AMY1AL3MBTL1POLB | |
| SCHEMBL3887393 | 0.74 | KMT2A (0.60) | KMT2AMEN1AMY1AL3MBTL1POLB | |
| SCHEMBL419547 | 0.73 | KMT2A (0.60) | KMT2AMEN1AMY1AL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065198-A2 | Detection and Treatment of Schizophrenia | TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) | 2012-03-15 | — | — | US | disclosed |
| US-20120065198-A2 | Detection and Treatment of Schizophrenia | TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065198-A2 | Detection and Treatment of Schizophrenia | GLO1, CBR1, AOX1 | KMT2A 1703/4885MEN1 4818/4885AMY1A 1713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.