Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.51 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.46 |
| ▸ | CTSA | P10619 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | EIF4E | P06730 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4204970 | 0.88 | ADORA3 (0.51) | HSP90AA1HSP90AB1ADORA3ALDH1A1HPGD | |
| SCHEMBL4214978 | 0.84 | ALOX15 (0.51) | HSP90AA1HSP90AB1ALOX15ADORA3ALDH1A1 | |
| SCHEMBL5015339 | 0.80 | ADORA3 (0.60) | HSP90AA1HSP90AB1ALOX15ADORA3ALDH1A1 | |
| SCHEMBL1735060 | 0.78 | CHRNA7 (0.50) | HSP90AA1HSP90AB1ALOX15ADORA3ALDH1A1 | |
| SCHEMBL4490553 | 0.78 | HSP90AA1 (0.58) | HSP90AA1HSP90AB1ADORA3ALDH1A1HPGD | |
| Trifluoroacetic Acid SCHEMBL4200702 | 0.77 | HSP90AA1 (0.51) | HSP90AA1HSP90AB1ADORA3ALDH1A1HPGD | |
| SCHEMBL4206708 | 0.76 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1ADORA3ALDH1A1HPGD | |
| SCHEMBL317192 | 0.76 | MCL1 (0.58) | ADORA3ALDH1A1HPGDADORA1KDM4E | |
| SCHEMBL2468801 | 0.75 | HSP90AA1 (0.54) | HSP90AA1HSP90AB1ADORA3ALDH1A1HPGD | |
| SCHEMBL14014334 | 0.75 | KDM4E (0.59) | ALDH1A1HPGDKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156646-A1 | PYRIDYLPHENOL COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
| EP-1921066-A1 | PYRIDYLPHENOL COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2008-05-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156646-A1 | PYRIDYLPHENOL COMPOUND AND USE THEREOF | GNRHR, PGR, MC1R | HSP90AA1 4006/4885HSP90AB1 3958/4885ALOX15 3597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.