SCHEMBL420633

SCHEMBL420633

COC(O)(Cc1ccccc1)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.50
HIF1A Q16665 1/20 0.50
FDPS P14324 1/20 0.44
ALDH1A1 P00352 4/20 0.44
RECQL P46063 2/20 0.44
PPARG P37231 1/20 0.44
PPARA Q07869 1/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
CYP1A2 P05177 2/20 0.44
TSHR P16473 1/20 0.41
PTPN2 P17706 1/20 0.41
PTPN1 P18031 1/20 0.41
PTPRA P18433 1/20 0.41
PTPRB P23467 1/20 0.41
SLC6A2 P23975 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
MMP8 P22894 3/20 0.41
CYP3A4 P08684 2/20 0.40
CES2 O00748 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28281268 0.82 ALDH1A1 (0.43) SMN1; SMN2HIF1AFDPSALDH1A1RECQL
SCHEMBL8694819 0.79 SMN1; SMN2 (0.48) SMN1; SMN2HIF1AFDPSALDH1A1RECQL
SCHEMBL934104 0.78 SMN1; SMN2 (0.52) SMN1; SMN2HIF1AFDPSALDH1A1RECQL
SCHEMBL2678813 0.78 SMN1; SMN2 (0.52) SMN1; SMN2HIF1AFDPSALDH1A1RECQL
SCHEMBL4595472 0.77 SMN1; SMN2 (0.60) SMN1; SMN2HIF1AFDPSALDH1A1RECQL
SCHEMBL3272549 0.77 PPARG (0.59) SMN1; SMN2HIF1AALDH1A1RECQLPPARG
SCHEMBL3272547 0.77 PPARG (0.59) SMN1; SMN2HIF1AALDH1A1RECQLPPARG
SCHEMBL9716385 0.76 MAPT (0.49) SMN1; SMN2FDPSCES1
SCHEMBL9620362 0.76 MAPT (0.49) SMN1; SMN2FDPSCES1
SCHEMBL9620173 0.76 MAPT (0.49) SMN1; SMN2FDPSCES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255989-A1 GLYCAN COMPOSITIONS AND USES THEREOF DSM NUTRITIONAL PRODUCTS LLC (US) 2023-08-17 US disclosed
US-11229660-B2 Glycan therapeutics and method of treating conditions associated with TMAO KALEIDO BIOSCIENCES, INC. (US) 2022-01-25 US disclosed
US-20210137956-A1 GLYCAN COMPOSITIONS AND USES THEREOF HERCULES CAPITAL, INC. 2021-05-13 US disclosed
US-20210113596-A1 GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF KALEIDO BIOSCIENCES, INC. (US) 2021-04-22 US disclosed
US-10881676-B2 Glycan therapeutics and related methods thereof KALEIDO BIOSCIENCES, INC. (US) 2021-01-05 US disclosed
US-10702542-B2 Glycan therapeutics and related methods thereof KALEIDO BIOSCIENCES, INC. (US) 2020-07-07 US disclosed
US-20200093851-A1 GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF HERCULES CAPITAL, INC. 2020-03-26 US disclosed
US-20200093845-A1 GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF HERCULES CAPITAL, INC. 2020-03-26 US disclosed
US-20190391092-A1 METABOLIC PROFILING WITH MAGNETIC RESONANCE MASS SPECTROMETRY (MRMS) Oregon Institute of Science and Medicine 2019-12-26 US disclosed
US-10314853-B2 Glycan therapeutics and related methods thereof KALEIDO BIOSCIENCES, INC. (US) 2019-06-11 US disclosed
US-20160213702-A1 GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF KALEIDO BIOSCIENCES, INC. (US) 2016-07-28 US disclosed
US-8926743-B2 Metal pigment, method for producing the same, and water base metallic resin composition including the same TOYO ALUMINIUM KABUSHIKI KAISHA (JP) 2015-01-06 US disclosed
US-20120129998-A1 METAL PIGMENT, METHOD FOR PRODUCING THE SAME, AND WATER BASE METALLIC RESIN COMPOSITION INCLUDING THE SAME TOYO ALUMINIUM KABUSHIKI KAISHA (JP) 2012-05-24 US disclosed
EP-2452985-A1 METALLIC PIGMENT, METHOD FOR PRODUCING SAME, AND AQUEOUS METALLIC RESIN COMPOSITION CONTAINING SAME Toyo Aluminium Kabushiki Kaisha (JP) 2012-05-16 EP disclosed
US-20120021061-A1 MEDICAL AND NUTRITIONAL FORMULATIONS COMVITA NEW ZEALAND LIMITED (NZ) 2012-01-26 US disclosed
US-20110287059-A1 HONEY ANALYSIS COMVITA NEW ZEALAND LIMITED (NZ) 2011-11-24 US disclosed
EP-2367444-A1 MEDICAL AND NUTRITIONAL FORMULATIONS Comvita New Zealand Limited (NZ) 2011-09-28 EP disclosed
EP-2368111-A1 HONEY ANALYSIS Comvita New Zealand Limited (NZ) 2011-09-28 EP disclosed
WO-2010082845-A1 HONEY ANALYSIS COMVITA NEW ZEALAND LIMITED (NZ) 2010-07-22 WO disclosed
WO-2010082846-A1 MEDICAL AND NUTRITIONAL FORMULATIONS COMVITA NEW ZEALAND LIMITED (NZ) 2010-07-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120021061-A1 MEDICAL AND NUTRITIONAL FORMULATIONS FABP6, NNT, IAPP SMN1; SMN2 1079/4885HIF1A 1181/4885FDPS 681/4885
US-20110287059-A1 HONEY ANALYSIS GLO1, GLMN, AGER SMN1; SMN2 3941/4885HIF1A 1571/4885FDPS 2715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.