Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.47 |
| ▸ | SCD | O00767 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2292116 | 0.86 | KDM4E (0.63) | SMN1; SMN2HPGDKDM4ENPC1RAB9A | |
| SCHEMBL6351828 | 0.81 | PTGES (0.62) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL4209179 | 0.77 | AKR1C2 (0.56) | SMN1; SMN2HPGDKDM4ENPC1RAB9A | |
| SCHEMBL2290679 | 0.76 | HPGD (0.78) | SMN1; SMN2HPGDKDM4ENPC1RAB9A | |
| SCHEMBL2290505 | 0.74 | KDM4E (0.67) | SMN1; SMN2HPGDKDM4ENPC1RAB9A | |
| SCHEMBL4213146 | 0.73 | AKR1C2 (0.61) | SMN1; SMN2HPGDNPC1RAB9ACYP1A2 | |
| SCHEMBL1307965 | 0.73 | AKR1C2 (0.77) | SMN1; SMN2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL2290164 | 0.73 | SMN1; SMN2 (0.76) | SMN1; SMN2NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL4217129 | 0.73 | AKR1C2 (0.54) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL1123502 | 0.73 | SMN1; SMN2 (0.61) | SMN1; SMN2HPGDKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247637-A1 | Novel Anthranilic Acid Derivatives | DEHMLOW HENRIETTA | 2009-10-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247637-A1 | Novel Anthranilic Acid Derivatives | GPR84, GPR88, HCAR1 | SMN1; SMN2 3904/4885HPGD 1058/4885KDM4E 3132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.