Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PHGDH | O43175 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2941972 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2RAB9ANPC1KDM4ETP53 | |
| SCHEMBL13515796 | 0.82 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9ANPC1KDM4ETP53 | |
| SCHEMBL2945609 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPK1RAB9ANPC1KDM4E | |
| SCHEMBL13664977 | 0.81 | ABL1 (0.43) | F10SMN1; SMN2MAPK1GRM5 | |
| SCHEMBL2942487 | 0.80 | SMN1; SMN2 (0.54) | F10SMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL4318072 | 0.80 | F10 (0.45) | F10SMN1; SMN2MAPK1GRM5MOK | |
| SCHEMBL4318062 | 0.80 | F10 (0.45) | F10SMN1; SMN2MAPK1GRM5MOK | |
| SCHEMBL2951090 | 0.79 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9ANPC1KDM4ETP53 | |
| SCHEMBL13665191 | 0.78 | SORT1 (0.57) | SMN1; SMN2RAB9ANPC1KDM4ETP53 | |
| SCHEMBL13665190 | 0.78 | SMN1; SMN2 (0.62) | SMN1; SMN2RAB9ANPC1KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023918-A1 | PROCESS FOR PREPARING 3-ACYLAMINOBENZOFURAN-2-CARBOXYLIC ACID DERIVATIVE | SEKI MASAHIKO | 2009-01-22 | — | — | US | disclosed |
| US-7439368-B2 | Process for producing 3-acylaminobenzofuran-2-carboxylic acid derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-10-21 | — | — | US | disclosed |
| US-20060173188-A1 | Process for producing 3-acylaminobenzofuran-2-carboxylic acid derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2006-08-03 | — | — | US | disclosed |
| EP-1640373-A1 | PROCESS FOR PRODUCING 3-ACYLAMINOBENZOFURAN-2-CARBOXYLIC ACID DERIVATIVE | TANABE SEIYAKU CO., LTD. (JP) | 2006-03-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173188-A1 | Process for producing 3-acylaminobenzofuran-2-carboxylic acid derivative | F12, F3, F11 | F10 8/4885SMN1; SMN2 4062/4885MAPK1 1361/4885 |
| US-20090023918-A1 | PROCESS FOR PREPARING 3-ACYLAMINOBENZOFURAN-2-CARBOXYLIC ACID DERIVATIVE | F12, F3, F11 | F10 9/4885SMN1; SMN2 3833/4885MAPK1 1246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.