Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24240345 | 0.86 | LMNA (0.62) | LMNAMAPTRAB9ANPSR1TSHR | |
| SCHEMBL15786414 | 0.81 | RAB9A (0.44) | LMNAMAPTRAB9ANPSR1TSHR | |
| SCHEMBL4202368 | 0.81 | LMNA (0.48) | LMNAMAPTRAB9ANPSR1TSHR | |
| SCHEMBL4209166 | 0.81 | PRMT1 (0.53) | LMNAMAPTRAB9ANPSR1TSHR | |
| SCHEMBL4210492 | 0.81 | MAPT (0.57) | LMNAMAPTRAB9ANPSR1TSHR | |
| SCHEMBL4213757 | 0.81 | ALDH1A1 (0.64) | LMNAMAPTRAB9ANPSR1TSHR | |
| SCHEMBL10053479 | 0.80 | ALDH1A1 (0.59) | LMNAMAPTRAB9ANPSR1TSHR | |
| SCHEMBL3298388 | 0.80 | ALDH1A1 (0.55) | LMNAMAPTRAB9ANPSR1TSHR | |
| SCHEMBL28188342 | 0.80 | ALDH1A1 (0.55) | LMNAMAPTRAB9ANPSR1TSHR | |
| SCHEMBL4202188 | 0.78 | CYP2D6 (0.54) | LMNAMAPTRAB9ANPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365544-A1 | SMALL MOLECULE INHIBITORS OF CALCIUM CHANNEL ACTIVITY AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH | 2023-11-16 | — | — | US | disclosed |
| US-20230365544-A1 | SMALL MOLECULE INHIBITORS OF CALCIUM CHANNEL ACTIVITY AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH | 2023-11-16 | — | — | US | disclosed |
| WO-2021231553-A1 | SMALL MOLECULE INHIBITORS OF CAV3.2 ACTIVITY AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2021-11-18 | — | — | WO | disclosed |
| US-7579480-B2 | Alkoxy-(tetrazol-1-yl)benzaldehyde compound and process for producing the same | TOYO KASEI KOGYO COMPANY LIMITED (JP) | 2009-08-25 | — | — | US | disclosed |
| US-20070060630-A1 | Alkoxy-(tetrazol-1-yl)benzaldehyde compound and process for producing the same | TOYO KASEI KOGYO COMPANY LIMITED (JP) | 2007-03-15 | — | — | US | disclosed |
| EP-1650198-A1 | ALKOXYTETRAZOL-1-YLBENZALDEHYDE COMPOUND AND PROCESS FOR PRODUCING THE SAME | Toyo Kasei Kogyo Company Limited (JP) | 2006-04-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365544-A1 | SMALL MOLECULE INHIBITORS OF CALCIUM CHANNEL ACTIVITY AND USES THEREOF | CACNA1G, CACNA1I, CACNG3 | LMNA 1895/4885MAPT 777/4885RAB9A 2529/4885 |
| US-20070060630-A1 | Alkoxy-(tetrazol-1-yl)benzaldehyde compound and process for producing the same | ALDH7A1, NAT1, ARSA | LMNA 2434/4885MAPT 3279/4885RAB9A 4394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.