Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 4/20 | 0.35 |
| ▸ | HTR7 | P34969 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4038524 | 0.83 | MMP2 (0.34) | MMP1MMP3MMP9 | |
| SCHEMBL4033157 | 0.75 | DRD2 (0.37) | ALDH1A1HTR1AHTR7MEN1KMT2A | |
| SCHEMBL4209294 | 0.71 | QPCT (0.42) | ALDH1A1MEN1KMT2ATSHRPKM | |
| SCHEMBL4208499 | 0.69 | GAA (0.47) | ALDH1A1KMT2ATSHRPKMGAA | |
| SCHEMBL4223317 | 0.68 | DRD2 (0.36) | ALDH1A1MMP1HTR1AHTR7DRD2 | |
| SCHEMBL4035688 | 0.68 | CA12 (0.39) | MMP9 | |
| SCHEMBL4212852 | 0.67 | FABP1 (0.45) | ALDH1A1PKMGAA | |
| SCHEMBL4208204 | 0.67 | ALDH1A1 (0.44) | ALDH1A1TSHRPKMGAA | |
| SCHEMBL4038496 | 0.67 | PSEN1 (0.39) | ALDH1A1MMP1MMP3MMP7MMP9 | |
| SCHEMBL1382974 | 0.67 | MEN1 (0.43) | ALDH1A1MMP1MMP3MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |