SCHEMBL4540807

SCHEMBL4540807

CCCCN[Si](CC)(OC)OC

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
CA12 O43570 2/20 0.32
CA14 Q9ULX7 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
ADH1B P00325 1/20 0.32
ADH1C P00326 1/20 0.32
ADH1A P07327 1/20 0.32
ADH7 P40394 1/20 0.32
CA7 P43166 1/20 0.32
ALDH1A1 P00352 1/20 0.32
ACHE P22303 1/20 0.31
EPHX1 P07099 1/20 0.31
TLR8 Q9NR97 1/20 0.31
TLR7 Q9NYK1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4199314 0.83 TSHR (0.35) TSHRCA12CA14CA1CA2
SCHEMBL4209307 0.83 TSHR (0.35) TSHRCA12CA14CA1CA2
SCHEMBL5182379 0.81 TSHR (0.33) TSHRCA12CA14CA1CA2
SCHEMBL4208547 0.79 ACHE (0.32) TSHRACHE
SCHEMBL5150822 0.74 CA12 (0.40) TSHRCA12CA14CA1CA2
SCHEMBL372486 0.74 TSHR (0.39) TSHRCA12CA14CA1CA2
SCHEMBL4210461 0.72 TSHR (0.38) TSHRCA12CA14CA1CA2
Hydrochloric Acid SCHEMBL6898632 0.72 EPHX1 (0.38) TSHRADH1BADH1CADH1AADH7
SCHEMBL21828516 0.70 TSHR (0.41) TSHRCA12CA14CA1CA2
SCHEMBL27032881 0.70 TSHR (0.48) TSHRCA12CA14CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090253873-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING POLYMER OR COPOLYMER OF OLEFIN USING THE SAME TOHO CATALYST CO., LTD (JP) 2009-10-08 US disclosed
EP-1829898-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING POLYMER OR COPOLYMER OF OLEFIN USING THE SAME Toho Catalyst Co., Ltd. (JP) 2007-09-05 EP disclosed