Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.54 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 6/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1008116 | 0.86 | LTB4R (0.61) | L3MBTL1MAPK1ALDH1A1KDM4ETSHR | |
| SCHEMBL27855936 | 0.84 | L3MBTL1 (0.53) | CYSLTR2CYSLTR1MMP13FAAHL3MBTL1 | |
| SCHEMBL2137203 | 0.83 | MAPK1 (0.66) | CYSLTR2CYSLTR1MMP13FAAHL3MBTL1 | |
| SCHEMBL1171676 | 0.83 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1FAAHL3MBTL1MAPK1 | |
| SCHEMBL19889912 | 0.83 | ALDH1A1 (0.54) | FAAHL3MBTL1MAPK1ALDH1A1LTA4H | |
| SCHEMBL24405135 | 0.83 | MAOB (0.60) | CYSLTR2CYSLTR1L3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL27855922 | 0.83 | L3MBTL1 (0.55) | CYSLTR2CYSLTR1MMP13L3MBTL1MAPK1 | |
| SCHEMBL13140901 | 0.82 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1MMP13FAAHL3MBTL1 | |
| SCHEMBL7041814 | 0.82 | L3MBTL1 (0.54) | CYSLTR2CYSLTR1L3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL1137350 | 0.82 | ALDH1A1 (0.67) | L3MBTL1MAPK1ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8563741-B2 | CDK inhibitors containing a zinc binding moiety | CURIS, INC. (US) | 2013-10-22 | — | — | US | disclosed |
| US-20090093507-A1 | CDK INHIBITORS CONTAINING A ZINC BINDING MOIETY | CURIS, INC. | 2009-04-09 | — | — | US | disclosed |
| WO-2009036016-A1 | CDK INHIBITORS CONTAINING A ZINC BINDING MOIETY | CURIS, INC. (US) | 2009-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093507-A1 | CDK INHIBITORS CONTAINING A ZINC BINDING MOIETY | CDK3, CDKL1, CDKL3 | CYSLTR2 4517/4885CYSLTR1 4419/4885MMP13 1739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.