Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 2/20 | 0.60 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.58 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13802264 | 0.91 | PTGDR2 (0.60) | THRATHRBPLA2G2APTGDR2MAPT | |
| SCHEMBL3000306 | 0.88 | PTGDR2 (0.68) | PLA2G2APTGDR2MAPTPLA2G1BAKR1C3 | |
| SCHEMBL4200412 | 0.87 | PTGDR2 (0.69) | THRATHRBPLA2G2APTGDR2MAPT | |
| SCHEMBL2002065 | 0.87 | PTGDR2 (0.53) | THRATHRBPLA2G2APTGDR2MAPT | |
| SCHEMBL2007815 | 0.87 | LMNA (0.58) | PLA2G2APTGDR2MAPTPLA2G1BAKR1C3 | |
| SCHEMBL2001190 | 0.86 | AKR1C3 (0.52) | THRATHRBPLA2G2APTGDR2MAPT | |
| SCHEMBL2002638 | 0.86 | PLA2G2A (0.63) | PLA2G2APTGDR2MAPTPLA2G1BAKR1C3 | |
| SCHEMBL13802427 | 0.85 | THRA (0.65) | THRATHRBPLA2G2APTGDR2PLA2G1B | |
| SCHEMBL2004289 | 0.85 | PLA2G2A (0.59) | THRATHRBPLA2G2APTGDR2PLA2G1B | |
| SCHEMBL2005905 | 0.85 | PLA2G2A (0.52) | PLA2G2APTGDR2MAPTPLA2G1BAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | APP, PSEN2, PSEN1 | THRA 3787/4885THRB 3290/4885PLA2G2A 409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.