SCHEMBL3000306

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2007815	0.89	LMNA (0.58)	PTGDR2AKR1C3AKR1C2LMNACYP1A2
	SCHEMBL4210031	0.88	THRA (0.60)	PTGDR2AKR1C3AKR1C2PLA2G2APLA2G1B
	SCHEMBL2001190	0.88	AKR1C3 (0.52)	PTGDR2AKR1C3AKR1C2LMNACYP1A2
	SCHEMBL2002638	0.87	PLA2G2A (0.63)	PTGDR2AKR1C3AKR1C2LMNACYP1A2
	SCHEMBL1998692	0.86	PTGDR2 (0.68)	PTGDR2AKR1C3AKR1C2LMNACYP1A2
	SCHEMBL2007754	0.86	AKR1C3 (0.51)	PTGDR2AKR1C3AKR1C2LMNACYP1A2
	SCHEMBL2003959	0.85	PLA2G2A (0.50)	PTGDR2AKR1C3AKR1C2LMNACYP1A2
	SCHEMBL16222859	0.84	AKR1C3 (0.48)	PTGDR2AKR1C3AKR1C2LMNAKDM4E
	SCHEMBL2005905	0.84	PLA2G2A (0.52)	PTGDR2AKR1C3AKR1C2LMNACYP1A2
	SCHEMBL4543998	0.83	PLA2G2A (0.50)	PTGDR2AKR1C3AKR1C2LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.