Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.91 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.91 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.91 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL1446288 | 1.00 | — | — | |
| Glycine SCHEMBL2116443 | 0.95 | — | — | |
| Glycine SCHEMBL391786 | 0.95 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2GABRR1LMNA | |
| Glycine SCHEMBL13169653 | 0.95 | — | — | |
| Glycine SCHEMBL6163 | 0.95 | — | — | |
| Glycine SCHEMBL93765 | 0.95 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2GABRR1LMNA | |
| Glycine SCHEMBL6675874 | 0.95 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2GABRR1LMNA | |
| Glycine SCHEMBL3640989 | 0.95 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2GABRR1LMNA | |
| Glycine SCHEMBL391027 | 0.95 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2GABRR1LMNA | |
| Glycine SCHEMBL30070584 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121574081-A | Preparation method of soluble selenium glycine | 郑州瑞普生物工程有限公司 | 2026-02-27 | — | — | CN | claimed |
| WO-2026044269-A1 | COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING ALZHEIMER'S DISEASE AND OTHER | SAFWAT SHERIF (US) | 2026-02-26 | — | — | WO | claimed |
| US-20240390415-A1 | MAGNESIUM/LITHIUM PREPARATIONS FOR NEUROPROTECTION AND NEUROTROPHIC BENEFITS | FP NUTRACEUTICALS LLC (US) | 2024-11-28 | — | — | US | claimed |
| CN-118902017-A | Mineral-enriched sausage and preparation method thereof | 新疆迎安农牧科技有限公司 | 2024-11-08 | — | — | CN | claimed |
| CN-116986953-B | Soil fertility-improving conditioner and preparation method thereof | 史丹利化肥扶余有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-116986953-A | Soil fertility-improving conditioner and preparation method thereof | 史丹利化肥扶余有限公司 | 2023-11-03 | — | — | CN | claimed |
| CN-116549462-A | Composition for improving sleep quality and application thereof | 湖南微木生物科技有限公司 | 2023-08-08 | — | — | CN | claimed |
| US-20220118006-A1 | MAGNESIUM/LITHIUM PREPARATIONS FOR NEUROPROTECTION AND NEUROTROPHIC BENEFITS | HANCOCK WHITNEY BANK | 2022-04-21 | — | — | US | claimed |
| US-11229667-B2 | Magnesium/lithium preparations for neuroprotection and neurotrophic benefits | FP NUTRACEUTICALS, LLC (US) | 2022-01-25 | — | — | US | claimed |
| CN-113243397-A | Preparation and application of special nutrition regulator for gramineous forage grass | 中科韶华(四川)牧业研究院有限公司 | 2021-08-13 | — | — | CN | claimed |
| CN-112657270-A | Nano water-soluble quantitative slow-release selenium-rich filter element for enhancing immunity and preventing cancers and diseases | 硒收力(杭州)科技有限公司 | 2021-04-16 | — | — | CN | claimed |
| CN-106798158-B | Chinese herbal medicine additive compound premix for laying hens and preparation method thereof | 河南科技学院 | 2021-01-22 | — | — | CN | claimed |
| US-10039765-B1 | Vitamin supplement compositions with enhanced bioavailability | TOOTHMAN MICHELLE ANN (US) | 2018-08-07 | — | — | US | claimed |
| US-20150132443-A1 | PURIFICATION PROGRAM | J/J Health Solutions, LLC | 2015-05-14 | — | — | US | claimed |
| CN-121574081-A | Preparation method of soluble selenium glycine | 郑州瑞普生物工程有限公司 | 2026-02-27 | — | — | CN | disclosed |
| WO-2026044269-A1 | COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING ALZHEIMER'S DISEASE AND OTHER | SAFWAT SHERIF (US) | 2026-02-26 | — | — | WO | disclosed |
| US-20250090455-A1 | SACCHARIDE-BASED ORAL MUCOADHESIVE DELIVERY SYSTEM FOR NUTRITIONAL AND NUTRACEUTICAL COMPOSITIONS | FP NUTRACEUTICALS, LLC (US) | 2025-03-20 | — | — | US | disclosed |
| EP-0514451-B1 | DIETARY SUPPLEMENTS COMPRISING VITAMINS AND MINERALS | LIFESCIENCE CORP (US) | 1997-01-15 | — | — | EP | disclosed |
| EP-0514451-A1 | DIETARY SUPPLEMENTS COMPRISING VITAMINS AND MINERALS. | UNIV TEXAS (US) | 1992-11-25 | — | — | EP | disclosed |
| WO-1991011117-A2 | DIETARY SUPPLEMENTS COMPRISING VITAMINS AND MINERALS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1991-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10039765-B1 | Vitamin supplement compositions with enhanced bioavailability | SLC19A1, SLC19A2, VKORC1L1 | GLRA1 3543/4885SLC6A9 322/4885OR51E2 4360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.