Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.57 |
| ▸ | MMP12 | P39900 | 1/20 | 0.57 |
| ▸ | GHSR | Q92847 | 5/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2280934 | 0.95 | PRKCA (0.51) | PRKCAMMP12GHSRNR1I2CYP3A4 | |
| SCHEMBL2277222 | 0.92 | PRKCA (0.59) | PRKCAMMP12NR1I2CYP3A4CYP2C9 | |
| SCHEMBL2280938 | 0.92 | PRKCA (0.53) | PRKCAMMP12GHSRNR1I2CYP3A4 | |
| SCHEMBL2278012 | 0.90 | PRKCA (0.54) | PRKCAMMP12NR1I2CNR2 | |
| SCHEMBL3684086 | 0.89 | PRKCA (0.60) | PRKCAMMP12NR1I2CYP3A4CYP2C9 | |
| SCHEMBL3814277 | 0.87 | PRKCA (0.48) | PRKCAMMP12PTGER1NR1I2CYP3A4 | |
| SCHEMBL393735 | 0.87 | PRKCA (0.75) | PRKCAMMP12NR1I2CYP3A4CYP2C9 | |
| SCHEMBL2276844 | 0.87 | PRKCA (0.52) | PRKCAMMP12NR1I2CYP3A4CYP2C9 | |
| SCHEMBL2280880 | 0.86 | PRKCA (0.56) | PRKCAMMP12NR1I2CYP3A4CYP2C9 | |
| SCHEMBL2278541 | 0.84 | PRKCA (0.47) | PRKCAMMP12NR1I2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048239-A1 | Therapeutic compounds | MSD ITALIA S.R.L. (IT) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048239-A1 | Therapeutic compounds | RRP1B, RCE1, CTSZ | PRKCA 4250/4885MMP12 2067/4885GHSR 3166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.