SCHEMBL4214647

SCHEMBL4214647

[CH2]C(C)(C)CCCC(C)C

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.47
CYP3A4 P08684 1/20 0.47
ALOX15 P16050 1/20 0.47
KMT2A Q03164 1/20 0.47
LMNA P02545 1/20 0.39
BLM P54132 1/20 0.33
PTPN2 P17706 1/20 0.32
PTPN1 P18031 1/20 0.32
CDC25B P30305 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17607589 0.92 LMNA (0.43) MEN1CYP3A4ALOX15KMT2ALMNA
SCHEMBL17607493 0.90 LMNA (0.42) MEN1CYP3A4ALOX15KMT2ALMNA
SCHEMBL28794358 0.90 LMNA (0.42) MEN1CYP3A4ALOX15KMT2ALMNA
SCHEMBL1971821 0.82
SCHEMBL28621256 0.81 MEN1 (0.50) MEN1CYP3A4ALOX15KMT2ALMNA
SCHEMBL7708604 0.81 MEN1 (0.32) MEN1CYP3A4ALOX15KMT2A
SCHEMBL19545639 0.79 MEN1 (0.39) MEN1CYP3A4ALOX15KMT2ALMNA
SCHEMBL17607530 0.79 MEN1 (0.31) MEN1CYP3A4ALOX15KMT2A
SCHEMBL306062 0.79 LMNA (0.48) MEN1CYP3A4ALOX15KMT2ALMNA
SCHEMBL29200722 0.78 MEN1 (0.47) MEN1CYP3A4ALOX15KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7312249-B2 Vitamin D analogues GALDERMA RESEARCH & DEVELOPMENT (FR) 2007-12-25 US claimed
US-20050182144-A1 Novel vitamin D analogues GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2005-08-18 US claimed
US-4142983-A PHTHALATE MIXTURES USEFUL AS LIQUID DIELECTRICS RHONE-POULENC INDUSTRIES (FR) 1979-03-06 US claimed
CN-117865922-A Formylcarboxylate coumarin compounds, methods of preparation and use thereof, and photoinitiator compositions containing same 湖北固润科技股份有限公司 2024-04-12 CN disclosed
CN-113347880-B Safety compositions comprising a pyridine carboxylate herbicide and a bisbenzoxazole acid 科迪华农业科技有限责任公司 2023-02-17 CN disclosed
CN-111278846-A Antimicrobial tetrapeptides 帝斯曼知识产权资产管理有限公司 2020-06-12 CN disclosed
CN-107074757-B The manufacturing method of trifluoromethyl alkylthio chemical combination object 组合化学工业株式会社 2019-05-03 CN disclosed
CN-105969543-B Flue dust cleaning agent after fire 江苏筑磊电子科技有限公司 2019-04-05 CN disclosed
CN-107108518-A Antibacterial imidazolium compounds 新加坡科技研究局 2017-08-29 CN disclosed
CN-107074757-A The manufacture method of trifluoromethyl alkylthio compound 组合化学工业株式会社 2017-08-18 CN disclosed
CN-105969543-A Smoke dust cleaning agent after fire hazards 江苏筑磊电子科技有限公司 2016-09-28 CN disclosed
US-20020019353-A1 Use of azalide antibiotic compositions for treating or preventing a bacterial or protozoal infection in mammals CANNING PETER CONNOR (US) 2002-02-14 US disclosed
US-5201937-A SALICYCLIC ACID DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 1993-04-13 US disclosed
EP-0151282-B1 OPTICALLY ACTIVE 3,4-BIS-(DIPHENYLPHOSPHINO)-PYRROLIDINE, RHODIUM COMPLEXES CONTAINING THEM AS CHIRAL LIGANDS, AND THEIR USE Degussa Aktiengesellschaft (DE) 1988-09-07 EP disclosed
EP-0151282-A1 Optically active 3,4-bis-(diphenylphosphino)-pyrrolidine, rhodium complexes containing them as chiral ligands, and their use Degussa Aktiengesellschaft (DE) 1985-08-14 EP disclosed
US-4142983-A PHTHALATE MIXTURES USEFUL AS LIQUID DIELECTRICS RHONE-POULENC INDUSTRIES (FR) 1979-03-06 US disclosed
US-4097521-A Manufacture of amidosulfonic acids BASF AKTIENGESELLSCHAFT (DT) 1978-06-27 US disclosed
US-4083849-A Process for preparation of 5-cyanopyrid-6-ones BASF AKTIENGESELLSCHAFT (DT) 1978-04-11 US disclosed
US-4026940-A CLEAVING TERT-BUTYL ESTER WITH STRONG ACID TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1977-05-31 US disclosed
US-3954826-A ANTIBACTERIAL INTERMEDIATES TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019353-A1 Use of azalide antibiotic compositions for treating or preventing a bacterial or protozoal infection in mammals PIGS, AZI2, AADAC MEN1 2400/4885CYP3A4 215/4885ALOX15 1747/4885
US-20050182144-A1 Novel vitamin D analogues CYP24A1, CYP2R1, VDR MEN1 1405/4885CYP3A4 305/4885ALOX15 530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.