Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 12/20 | 0.63 |
| ▸ | PGR | P06401 | 6/20 | 0.63 |
| ▸ | AR | P10275 | 2/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.63 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.63 |
| ▸ | CNR1 | P21554 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.58 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 3/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MLNR | O43193 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4218012 | 1.00 | NR3C1 (0.63) | NR3C1PGRARPTGS1NR3C2 | |
| SCHEMBL4218105 | 0.94 | NR3C1 (0.63) | NR3C1PGRARPTGS1NR3C2 | |
| SCHEMBL4222810 | 0.93 | NR3C1 (0.62) | NR3C1PGRARPTGS1NR3C2 | |
| SCHEMBL15225955 | 0.92 | NR3C1 (0.61) | NR3C1PGRARPTGS1NR3C2 | |
| SCHEMBL15225449 | 0.89 | NR3C1 (0.80) | NR3C1PGRARPTGS1NR3C2 | |
| SCHEMBL15225810 | 0.89 | NR3C1 (0.67) | NR3C1PGRARNR3C2CYP3A4 | |
| SCHEMBL3999196 | 0.88 | NR3C1 (0.78) | NR3C1PGRARPTGS1NR3C2 | |
| SCHEMBL4008052 | 0.88 | NR3C1 (0.78) | NR3C1PGRARPTGS1NR3C2 | |
| SCHEMBL27255186 | 0.88 | NR3C1 (0.78) | NR3C1PGRARPTGS1NR3C2 | |
| SCHEMBL4218885 | 0.87 | NR3C1 (0.60) | NR3C1PGRARPTGS1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054388-A1 | NOVEL 11 BETA-HYDROXYANDROSTA-4-ENE-3-ONES | SUN PHARMA ADVANCE RESEARCH COMPANY (IN) | 2009-02-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054388-A1 | NOVEL 11 BETA-HYDROXYANDROSTA-4-ENE-3-ONES | HSD11B1, HSD3B1, HSD3B2 | NR3C1 37/4885PGR 146/4885AR 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.