Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | TAS2R31 | P59538 | 2/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30366152 | 1.00 | NPC1 (0.64) | NPC1RAB9ATAS2R31PTGS2POLB | |
| SCHEMBL905614 | 0.82 | NPC1 (0.73) | NPC1RAB9ATAS2R31PTGS2POLB | |
| Dihydrooroxylin A SCHEMBL31682921 | 0.78 | NPC1 (1.00) | NPC1RAB9ATAS2R31POLBABCB1 | |
| SCHEMBL27775449 | 0.78 | NPC1 (0.82) | NPC1RAB9ATAS2R31POLBABCG2 | |
| Dihydrooroxylin A SCHEMBL12067042 | 0.78 | NPC1 (1.00) | NPC1RAB9ATAS2R31POLBABCB1 | |
| SCHEMBL30716844 | 0.77 | NPC1 (0.77) | NPC1RAB9ATAS2R31PTGS2POLB | |
| SCHEMBL4218778 | 0.76 | ACHE (0.45) | NPC1RAB9APOLBACHEKDM4E | |
| SCHEMBL5551104 | 0.74 | NPC1 (0.69) | NPC1RAB9ATAS2R31PTGS2POLB | |
| SCHEMBL5084370 | 0.74 | CYP1A1 (0.77) | NPC1RAB9ATAS2R31PTGS2POLB | |
| SCHEMBL382207 | 0.73 | TAS2R31 (0.79) | NPC1RAB9ATAS2R31PTGS2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9585928-B2 | Agave syrup extract having anticancer activity | INSTITUTO TECHNOLOGICO Y DE ESTUDIOS SUPERIORES DE MONTERREY (MX) | 2017-03-07 | — | — | US | disclosed |
| US-9585928-B2 | Agave syrup extract having anticancer activity | INSTITUTO TECHNOLOGICO Y DE ESTUDIOS SUPERIORES DE MONTERREY (MX) | 2017-03-07 | — | — | US | disclosed |
| US-20130209588-A1 | AGAVE SYRUP EXTRACT HAVING ANTICANCER ACTIVITY | AGMEL S.A. DE C.V. (MX) | 2013-08-15 | — | — | US | disclosed |
| US-20130209588-A1 | AGAVE SYRUP EXTRACT HAVING ANTICANCER ACTIVITY | AGMEL S.A. DE C.V. (MX) | 2013-08-15 | — | — | US | disclosed |
| US-8470858-B2 | Agave syrup extract having anticancer activity | OZUNA, ALBINO VARGAS (MX) | 2013-06-25 | — | — | US | disclosed |
| US-20090124685-A1 | AGAVE SYRUP EXTRACT HAVING ANTICANCER ACTIVITY | OZUNA, ALBINO VARGAS (MX) | 2009-05-14 | — | — | US | disclosed |