Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 9/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4232907 | 0.86 | EGLN1 (0.40) | EGLN1LDHALDHB | |
| SCHEMBL4231053 | 0.83 | CXCL8 (0.32) | SCN9ALMNATSHR | |
| SCHEMBL4231017 | 0.78 | NPY5R (0.38) | SCN9ALMNACYP2C19 | |
| SCHEMBL4229598 | 0.76 | KDM4E (0.34) | LMNAHPGD | |
| SCHEMBL4225596 | 0.72 | KMT2A (0.35) | CYP2C19LDHALDHBTSHR | |
| SCHEMBL4219785 | 0.71 | GLP1R (0.42) | LMNAHPGDTSHR | |
| SCHEMBL4225599 | 0.70 | MAT2A (0.33) | LMNACYP2C19TSHR | |
| SCHEMBL4219852 | 0.66 | LMNA (0.35) | SCN9ALMNACYP2C19TSHR | |
| SCHEMBL4225977 | 0.64 | HSP90AA1 (0.45) | LMNAHPGD | |
| SCHEMBL4231674 | 0.63 | LMNA (0.39) | LMNAHPGDCYP2C9CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2092824-A1 | Heterocyclyl pyrimidines | Bayer CropScience AG (DE) | 2009-08-26 | — | — | EP | disclosed |
| EP-2092824-A1 | Heterocyclyl pyrimidines | Bayer CropScience AG (DE) | 2009-08-26 | — | — | EP | disclosed |