Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4219866 | 1.00 | MMP12 (0.42) | MMP12MMP13IDO1MAPTHDAC1 | |
| SCHEMBL1839910 | 1.00 | MMP12 (0.42) | MMP12MMP13IDO1MAPTHDAC1 | |
| SCHEMBL1841168 | 0.84 | L3MBTL1 (0.37) | MMP12MMP13MAPTALDH1A1HTR1A | |
| SCHEMBL379427 | 0.82 | ALDH1A1 (0.55) | IDO1MAPTALDH1A1LMNATSHR | |
| SCHEMBL875547 | 0.80 | PPARG (0.53) | IDO1MAPTHDAC1TP53ALDH1A1 | |
| SCHEMBL15733064 | 0.78 | PTPN1 (0.52) | PTPN1 | |
| SCHEMBL379534 | 0.76 | MMP2 (0.57) | MMP13 | |
| SCHEMBL4923108 | 0.76 | MMP2 (0.57) | MMP13 | |
| SCHEMBL379128 | 0.76 | MMP2 (0.57) | MMP13 | |
| SCHEMBL379943 | 0.76 | MMP2 (0.57) | MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074093-A2 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008023336-A2 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2008-02-28 | — | — | WO | disclosed |