Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 7/20 | 0.33 |
| ▸ | RXRG | P48443 | 3/20 | 0.33 |
| ▸ | RXRB | P28702 | 3/20 | 0.33 |
| ▸ | RARB | P10826 | 3/20 | 0.32 |
| ▸ | RARG | P13631 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31294415 | 0.78 | RARA (0.36) | RARARXRARXRGRXRBRARB | |
| Hydrochloric Acid SCHEMBL31265039 | 0.71 | — | — | |
| SCHEMBL11599145 | 0.69 | RXRA (0.42) | RARARXRARXRGRXRBRARB | |
| Hydrochloric Acid SCHEMBL31265023 | 0.68 | RXRA (0.31) | RARARXRARXRGRXRBRARB | |
| Hydrochloric Acid SCHEMBL4219944 | 0.67 | RARB (0.33) | RARARXRARXRGRXRBRARB | |
| SCHEMBL21244356 | 0.67 | RXRA (0.33) | RARARXRARXRGRXRBRARB | |
| SCHEMBL31265037 | 0.66 | RXRA (0.32) | RARARXRARXRGRXRBRARB | |
| SCHEMBL25129965 | 0.66 | RXRA (0.45) | RARARXRARXRGRXRBRARB | |
| SCHEMBL24085013 | 0.64 | ALDH1A1 (0.33) | — | |
| SCHEMBL23445125 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9023906-B2 | Propylene-based copolymer, propylene-based copolymer composition, molded product thereof and foamed product thereof, and production process therefor | MITSUI CHEMICALS, INC. (JP) | 2015-05-05 | — | — | US | disclosed |
| US-20140088214-A1 | PROPYLENE-BASED COPOLYMER, PROPYLENE-BASED COPOLYMER COMPOSITION, MOLDED PRODUCT THEREOF AND FOAMED PRODUCT THEREOF, AND PRODUCTION PROCESS THEREFOR | MITSUI CHEMICALS, INC. | 2014-03-27 | — | — | US | disclosed |
| EP-2711380-A1 | PROPYLENE COPOLYMER AND PROPYLENE COPOLYMER COMPOSITION, MOLDING AND FOAM THEREOF, AND PROCESSES FOR PRODUCING SAID MOLDING AND FOAM | Mitsui Chemicals, Inc. (JP) | 2014-03-26 | — | — | EP | disclosed |
| EP-2077283-A1 | ETHYLENE COPOLYMER, COMPOSITION CONTAINING THE COPOLYMER, AND USE OF THE SAME | Mitsui Chemicals, Inc. (JP) | 2009-07-08 | — | — | EP | disclosed |