Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5960697 | 0.67 | SMN1; SMN2 (0.34) | NAMPT | |
| SCHEMBL13715702 | 0.65 | — | — | |
| SCHEMBL12992825 | 0.64 | — | — | |
| SCHEMBL7874522 | 0.64 | HSP90AA1 (0.33) | NAMPT | |
| SCHEMBL17733547 | 0.63 | NAMPT (0.33) | NAMPT | |
| SCHEMBL17733614 | 0.63 | L3MBTL1 (0.33) | NAMPT | |
| SCHEMBL17733595 | 0.62 | NAMPT (0.33) | NAMPT | |
| SCHEMBL20342898 | 0.62 | NAMPT (0.33) | NAMPT | |
| SCHEMBL22312264 | 0.62 | TDP1 (0.33) | — | |
| SCHEMBL13591827 | 0.62 | HSP90AA1 (0.33) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009124086-A2 | ANTIBACTERIAL DRUG FOR TREATMENT OF STAPHYLOCOCCUS AUREUS AND OTHER GRAM-POSITIVE BACTERIAL INFECTIONS | SIGA TECHNOLOGIES, INC. (US) | 2009-10-08 | — | — | WO | claimed |
| WO-2009124086-A2 | ANTIBACTERIAL DRUG FOR TREATMENT OF STAPHYLOCOCCUS AUREUS AND OTHER GRAM-POSITIVE BACTERIAL INFECTIONS | SIGA TECHNOLOGIES, INC. (US) | 2009-10-08 | — | — | WO | disclosed |