SCHEMBL4222893

SCHEMBL4222893

CCCCCCCCCCCCC(CC(O)=S)C(O)=S

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ GPR84 Q9NQS5 7/20 0.42
▸ CA2 P00918 2/20 0.42
▸ GRIK1 P39086 2/20 0.42
▸ GRIK2 Q13002 2/20 0.42
▸ FFAR1 O14842 1/20 0.41
▸ LMNA P02545 1/20 0.40
▸ MAPT P10636 1/20 0.39
▸ LCK P06239 1/20 0.39
▸ PPARD Q03181 1/20 0.39
▸ ZDHHC20 Q5W0Z9 1/20 0.39
▸ ZDHHC2 Q9UIJ5 1/20 0.39
▸ SLC1A2 P43004 1/20 0.39
▸ SLC1A1 P43005 1/20 0.39
▸ MAPK1 P28482 1/20 0.38
▸ FFAR4 Q5NUL3 1/20 0.37
▸ ACE2 Q9BYF1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4228086 1.00 GPR84 (0.42) GPR84CA2GRIK1GRIK2FFAR1
SCHEMBL4373374 1.00 GPR84 (0.42) GPR84CA2GRIK1GRIK2FFAR1
SCHEMBL4227946 1.00 GPR84 (0.42) GPR84CA2GRIK1GRIK2FFAR1
SCHEMBL9345012 1.00 GPR84 (0.42) GPR84CA2GRIK1GRIK2FFAR1
SCHEMBL4227274 1.00 GPR84 (0.42) GPR84CA2GRIK1GRIK2FFAR1
SCHEMBL4376984 1.00 GPR84 (0.42) GPR84CA2GRIK1GRIK2FFAR1
SCHEMBL4378421 1.00 GPR84 (0.42) GPR84CA2GRIK1GRIK2FFAR1
SCHEMBL11437891 0.91 CA2 (0.45) GPR84CA2GRIK1GRIK2SLC1A2
SCHEMBL10964155 0.87 CA2 (0.48) GPR84CA2GRIK1GRIK2FFAR1
SCHEMBL8324703 0.87 CA2 (0.48) GPR84CA2GRIK1GRIK2FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1473592-B1 Image display medium and image forming method RICOH KK (JP) 2009-02-11 — — EP disclosed
EP-1234681-B1 Reversible thermosensitive recording medium and image processing method using the same RICOH KK (JP) 2007-04-18 — — EP disclosed
EP-1473592-A1 Image display medium and image forming method Ricoh Company, Ltd. (JP) 2004-11-03 — — EP disclosed
US-20040171780-A1 Esterification of a polyol and dicarboxylic acid ; acrylation SURFACE SPECIALTIES, S.A. (BE) 2004-09-02 — — US disclosed
US-6770592-B2 Reversible thermosensitive recording medium and image processing method using the same RICOH COMPANY, LTD. (JP) 2004-08-03 — — US disclosed
EP-1421134-A1 POLYMER COMPOSITIONS AND USES THEREOF UCB, S.A. (BE) 2004-05-26 — — EP disclosed
US-6734138-B2 SURFACE HAVING A SPECIFIED TEN-POINT MEAN ROUGHNESS (RZ) AND/OR A GIVEN RATIO SM/RZ, WHERE SM IS AVERAGE PEAK-TO-PEAK LENGTH OF THE SURFACE OF THE RECORDING MATERIAL; REVERSIBLY CHANGES ITS COLOR WHEN HEATED AND THEN COOLED RICOH COMPANY, LTD. (JP) 2004-05-11 — — US disclosed
EP-1211090-B1 Reversible thermosensitive recording material, and image recording and erasing method using the recording material RICOH KK (JP) 2004-05-06 — — EP disclosed
US-20040014931-A1 Compositions for lithographic or flexographic inks are disclosed comprising at least one compound of Formula 1: for polyester acrylates SURFACE SPECIALTIES, S.A. (BE) 2004-01-22 — — US disclosed
US-6613715-B2 Comprising a support, a reversible thermosensitive recording layer of which color tone is reversibly changeable with the application of heat thereto to change the temperature and a printing layer which bears a printed image RICOH COMPANY, LTD. (JP) 2003-09-02 — — US disclosed
US-6410478-B1 A LAYER COMPRISING COLORING AGENT(LEUCO DYE), COLOR DEVELOPERS AND DECOLORING PROMOTERS COATED ON A SUPPORT; IMAGE DISPLAYS AND AS A REWRITABLE PAPER RICOH COMPANY, LTD. (JP) 2002-06-25 — — US disclosed
EP-1211090-A1 Reversible thermosensitive recording material, and image recording and erasing method using the recording material Ricoh Company, Ltd. (JP) 2002-06-05 — — EP disclosed
US-20010029236-A1 Method of using reversible thermosensitive recording medium and the reversible thermosensitive recording medium RICOH COMPANY, LTD. (JP) 2001-10-11 — — US disclosed
US-5582760-A POLYOL ESTER BASED TURBINE OIL; OXIDATION AND CORROSION RESISTANCE, SILICON SEAL COMPATIBILITY EXXON RESEARCH AND ENGINEERING COMPANY (US) 1996-12-10 — — US disclosed
US-4670163-A HALOHYDROXYALKYLTHIO-SUBSTITUTED OR DIHYDROXYALKYLTHIO-SUBSTITUTED POLYCARBOXYLIC ACIDS AND SALTS PHILLIPS PETROLEUM COMPANY (US) 1987-06-02 — — US disclosed
EP-0024375-B1 YARN TREATING COMPOSITION FOR HIGH-SPEED FRICTION DRAW-FALSE TWIST TEXTURING AND A FILAMENTARY YARN TREATED WITH THE SAME TEIJIN LIMITED (JP) 1983-02-23 — — EP disclosed
US-4351738-A ETHYLENE OXIDE-PROPYLENE OXIDE COPOLYMER TEIJIN LIMITED (JP) 1982-09-28 — — US disclosed
EP-0024375-A1 Yarn treating composition for high-speed friction draw-false twist texturing and a filamentary yarn treated with the same TEIJIN LIMITED (JP) 1981-03-04 — — EP disclosed
US-4234678-A DEVELOPMENT INHIBITORS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1980-11-18 — — US disclosed
US-4152515-A PHOSPHOROUS-FREE LEVER BROTHERS COMPANY (US) 1979-05-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171780-A1 Esterification of a polyol and dicarboxylic acid ; acrylation ACSL3, ACSL4, ACSL1 GPR84 3298/4885CA2 3662/4885GRIK1 885/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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