Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 11/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4222927 | 1.00 | DGAT1 (0.56) | DGAT1KMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL4222925 | 1.00 | DGAT1 (0.56) | DGAT1KMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL4226864 | 0.91 | DGAT1 (0.69) | DGAT1KMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL4226856 | 0.91 | DGAT1 (0.69) | DGAT1KMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL4226860 | 0.91 | DGAT1 (0.69) | DGAT1KMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL4886391 | 0.80 | DGAT1 (0.77) | DGAT1KMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL4890050 | 0.79 | DGAT1 (0.58) | DGAT1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL4885534 | 0.77 | DGAT1 (0.84) | DGAT1KMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL4230980 | 0.77 | DGAT1 (0.71) | DGAT1KMT2AMEN1NPC1LMNA | |
| SCHEMBL4230984 | 0.77 | DGAT1 (0.71) | DGAT1KMT2AMEN1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215780-A1 | Preparation and Use of Aryl Alkyl Acid Derivatives for the Treatment of Obesity | BAYER PHARMACEUTICALS CORPORATION (US) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215780-A1 | Preparation and Use of Aryl Alkyl Acid Derivatives for the Treatment of Obesity | FABP4, GPR119, LIPC | DGAT1 34/4885KMT2A 627/4885MEN1 4348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.