Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851460 | 0.88 | LMNA (0.37) | LMNASMN1; SMN2HTTESR1CYP2D6 | |
| SCHEMBL9862015 | 0.87 | HCAR2 (0.35) | LMNACYP2D6RAB9ANPC1MEN1 | |
| SCHEMBL4224940 | 0.85 | CYP2D6 (0.38) | LMNASMN1; SMN2HTTEGFRERBB2 | |
| SCHEMBL8761490 | 0.82 | CYP2D6 (0.36) | LMNASMN1; SMN2HTTEGFRERBB2 | |
| SCHEMBL10498335 | 0.79 | HCAR2 (0.33) | — | |
| SCHEMBL8972266 | 0.78 | CYP2D6 (0.33) | EGFRERBB2CYP2D6CYP2C9HIF1A | |
| SCHEMBL9862102 | 0.77 | HCAR2 (0.32) | — | |
| SCHEMBL9847991 | 0.76 | EPHX1 (0.32) | LMNASMN1; SMN2HTTCYP2D6CYP2C9 | |
| SCHEMBL9847930 | 0.75 | CYP2D6 (0.35) | CYP2D6CYP2C9HIF1AMEN1KMT2A | |
| SCHEMBL9862043 | 0.74 | MAPK1 (0.39) | LMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423767-A2 | Thermoplastic resin composition and method for preparing the same | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1991-04-24 | — | — | EP | disclosed |