SCHEMBL422596

SCHEMBL422596

Nc1cccc[n+]1C=Cc1cccc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CHAT P28329 6/20 0.50
▸ HDAC8 Q9BY41 1/20 0.43
▸ HDAC6 Q9UBN7 1/20 0.43
▸ RXRA P19793 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10706694 0.72 CHAT (0.62) CHATHDAC8HDAC6RXRA
SCHEMBL10706687 0.72 CHAT (0.62) CHATHDAC8HDAC6RXRA
SCHEMBL10706700 0.72 CHAT (0.62) CHATHDAC8HDAC6RXRA
SCHEMBL4666033 0.72 MAOB (0.43) CHATHDAC8HDAC6
SCHEMBL10437275 0.70 CHAT (0.60) CHATHDAC8HDAC6RXRA
SCHEMBL10437274 0.70 CHAT (0.60) CHATHDAC8HDAC6RXRA
SCHEMBL3932039 0.70 ALDH1A1 (0.58) CHATHDAC8HDAC6RXRA
SCHEMBL4925730 0.69 RXRA (0.53) CHATHDAC8HDAC6RXRA
SCHEMBL29399914 0.68 RXRA (0.57) CHATHDAC8HDAC6RXRA
SCHEMBL4626591 0.68 RXRA (0.57) CHATHDAC8HDAC6RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210116488-A1 Quantum Converting Nanoparticles as In Vivo and In Situ Optical Electric Field Sensors THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2021-04-22 — — US claimed
US-10405750-B2 Nonradiative voltage-sensitive dye for imaging neuronal action potential WASHINGTON UNIVERSITY (US) 2019-09-10 — — US claimed
US-20190235002-A1 Quantum Converting Nanoparticles as In Vivo and In Situ Optical Electric Field Sensors THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2019-08-01 — — US claimed
US-20170268031-A1 METHODS FOR BACTERIOPHAGE DETECTION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-09-21 — — US claimed
WO-2016134469-A1 APPARATUS FOR MEASUREMENT OF OPTICAL TRANSMISSION USING FLUORESCENCE RADIATION ASTENJOHNSON, INC. (US) 2016-09-01 — — WO claimed
US-20160242651-A1 NONRADIATIVE VOLTAGE-SENSITIVE DYE FOR IMAGING NEURONAL ACTION POTENTIAL WASHINGTON UNIVERSITY 2016-08-25 — — US claimed
WO-2016018678-A1 METHODS FOR BACTERIOPHAGE DETECTION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-02-04 — — WO claimed
US-20110028837-A1 Photodynamic-based myocardial mapping device and method ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. 2011-02-03 — — US claimed
EP-2254463-A2 PHOTODYNAMIC-BASED MYOCARDIAL MAPPING DEVICE AND METHOD St. Jude Medical, Atrial Fibrillation Division, Inc. (US) 2010-12-01 — — EP claimed
WO-2009124220-A2 PHOTODYNAMIC-BASED MYOCARDIAL MAPPING DEVICE AND METHOD ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. (US) 2009-10-08 — — WO claimed
US-20070281330-A1 Method for Examining the Activity of Ion Channels EVOTEC AG (DE) 2007-12-06 — — US claimed
EP-1711832-A1 METHOD FOR EXAMINING THE ACTIVITY OF ION CHANNELS Evotec AG (DE) 2006-10-18 — — EP claimed
WO-2006037226-A1 USE OF QUANTUM DOTS FOR BIOLOGICAL LABELS AND SENSORS MCGILL UNIVERSITY (CA) 2006-04-13 — — WO claimed
WO-2005069008-A1 METHOD FOR EXAMINING THE ACTIVITY OF ION CHANNELS EVOTEC AG (DE) 2005-07-28 — — WO claimed
US-20260014561-A1 METHODS AND APPARATUS FOR SINGLE BIOLOGICAL NANOPARTICLE ANALYSIS UNIV WASHINGTON (US) 2026-01-15 — — US disclosed
US-12447469-B2 Methods and apparatus for single biological nanoparticle analysis UNIVERSITY OF WASHINGTON (US) 2025-10-21 — — US disclosed
US-20250101504-A1 METHODS OF MEASURING MISLOCALIZATION OF AN ANALYTE 10X GENOMICS, INC. 2025-03-27 — — US disclosed
US-20050153128-A1 Product packaging including digital data SELINFREUND RICHARD H (US) 2005-07-14 — — US disclosed
US-6472163-B1 >100 REGIONS WITH >/= A BIOLOGICAL CELL ON A CONTINUOUS BASE AT AVERAGE DENSITY OF >/=10 REGIONS PER SQUARE CM, A REACTION RESULTS IN AN OPTICALLY DETECTABLE SIGNAL CHANGE OVER TIME, AUTOMATICALLY MONITORING CHANGES TO INDICATE DESIRED SIGNAL KAIROS SCIENTIFIC, INC. 2002-10-29 — — US disclosed
WO-2001066788-A2 COLORIMETRIC MUTAGENIZED ENZYME SCREENING IN MICROCOLONIES KAIROS SCIENTIFIC, INC. (US) 2001-09-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014561-A1 METHODS AND APPARATUS FOR SINGLE BIOLOGICAL NANOPARTICLE ANALYSIS CD63, SELL, LAMP2 CHAT 1287/4885HDAC8 3392/4885HDAC6 1598/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback