Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | RECQL | P46063 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | SLCO2B1 | O94956 | 3/20 | 0.60 |
| ▸ | XDH | P47989 | 3/20 | 0.60 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.60 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.60 |
| ▸ | APEX1 | P27695 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | CASP1 | P29466 | 2/20 | 0.60 |
| ▸ | CASP7 | P55210 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4226904 | 1.00 | MEN1 (0.60) | MEN1KMT2AKDM4EMAPTHSD17B10 | |
| SCHEMBL10859102 | 0.87 | KDM4E (0.67) | MEN1KMT2AKDM4EMAPTHSD17B10 | |
| SCHEMBL23158626 | 0.83 | POLH (0.68) | MEN1KMT2AKDM4EMAPTHSD17B10 | |
| SCHEMBL4232105 | 0.81 | POLH (0.58) | MEN1KMT2AKDM4EMAPTHSD17B10 | |
| SCHEMBL34716 | 0.80 | KDM4E (0.73) | MEN1KMT2AKDM4EMAPTHSD17B10 | |
| SCHEMBL29512814 | 0.80 | KDM4E (0.73) | MEN1KMT2AKDM4EMAPTHSD17B10 | |
| SCHEMBL22548985 | 0.80 | KDM4E (0.60) | MEN1KMT2AKDM4EMAPTHSD17B10 | |
| SCHEMBL4286345 | 0.80 | MEN1 (0.65) | MEN1KMT2AKDM4EMAPTHSD17B10 | |
| SCHEMBL4231485 | 0.79 | POLH (0.58) | MEN1KMT2AKDM4EMAPTHSD17B10 | |
| SCHEMBL22548987 | 0.78 | KDM4E (0.63) | MEN1KMT2AKDM4EMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090182133-A1 | BENZOPYRANONE DERIVATIVES AND THEIR USE AS ANTI-VIRAL AGENTS | SINGAPORE POLYTECHNIC | 2009-07-16 | — | — | US | disclosed |
| EP-1968569-A4 | BENZOPYRANONE DERIVATIVES AND THEIR USE AS ANTI-CORONAVIRAL AGENTS | SINGAPORE POLYTECHNIC (SG) | 2008-12-17 | — | — | EP | disclosed |
| EP-1968569-A1 | BENZOPYRANONE DERIVATIVES AND THEIR USE AS ANTI-CORONAVIRAL AGENTS | Singapore Polytechnic (SG) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007075145-A1 | BENZOPYRANONE DERIVATIVES AND THEIR USE AS ANTI-CORONAVIRAL AGENTS | SINGAPORE POLYTECHNIC (SG) | 2007-07-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090182133-A1 | BENZOPYRANONE DERIVATIVES AND THEIR USE AS ANTI-VIRAL AGENTS | SARS1, MAVS, ACE2 | MEN1 4730/4885KMT2A 3631/4885KDM4E 1537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.