Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 10/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 5/20 | 0.35 |
| ▸ | HTR2A | P28223 | 5/20 | 0.35 |
| ▸ | DRD3 | P35462 | 4/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4230615 | 0.78 | CHRM1 (0.51) | CHRM1DRD2HTR2ACHRM2CHRM4 | |
| SCHEMBL4235669 | 0.78 | CHRM1 (0.55) | CHRM1CHRM4CHRM5MCHR1 | |
| SCHEMBL4049143 | 0.75 | CHRM1 (0.35) | CHRM1L3MBTL1DRD2HTR2ADRD3 | |
| SCHEMBL1554091 | 0.75 | CHRM1 (0.49) | CHRM1DRD2HTR2ACHRM2CHRM4 | |
| SCHEMBL4236355 | 0.74 | CHRM1 (0.43) | CHRM1DRD2HTR2ADRD3CCR1 | |
| SCHEMBL4051360 | 0.74 | SIGMAR1 (0.47) | CHRM1HRH3L3MBTL1DRD2HTR2A | |
| SCHEMBL4228778 | 0.73 | CHRM1 (0.43) | CHRM1HRH3L3MBTL1DRD2ADRA1A | |
| SCHEMBL4231625 | 0.71 | CHRM1 (0.53) | CHRM1CHRM4CHRM5MCHR1 | |
| SCHEMBL4049616 | 0.71 | SIGMAR1 (0.49) | CHRM1DRD2HTR2ACHRM2CHRM4 | |
| SCHEMBL4225067 | 0.70 | CHRM1 (0.35) | CHRM1DRD2HTR2ACHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106534-A1 | NOVEL HETEROCYCLIC CARBOXAMIDES AS M1 AGONISTS | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106534-A1 | NOVEL HETEROCYCLIC CARBOXAMIDES AS M1 AGONISTS | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | disclosed |