Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.62 |
| ▸ | POLB | P06746 | 9/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Furfural SCHEMBL896784 | 0.91 | ALDH1A1 (0.69) | ALDH1A1POLBTDP1MAPTL3MBTL1 | |
| Furfural SCHEMBL3943284 | 0.84 | ALDH1A1 (0.55) | ALDH1A1POLBTDP1MAPTL3MBTL1 | |
| Furfural SCHEMBL2203874 | 0.81 | ALDH1A1 (0.78) | ALDH1A1POLBTDP1MAPTL3MBTL1 | |
| Furfural SCHEMBL28172662 | 0.81 | ALDH1A1 (0.64) | ALDH1A1POLBTDP1MAPTL3MBTL1 | |
| Furfural SCHEMBL11318425 | 0.80 | ALDH1A1 (0.75) | ALDH1A1POLBTDP1MAPTL3MBTL1 | |
| Furfural SCHEMBL153707 | 0.80 | ALDH1A1 (0.75) | ALDH1A1POLBTDP1MAPTL3MBTL1 | |
| Furfural SCHEMBL28836554 | 0.79 | ALDH1A1 (0.82) | ALDH1A1POLBTDP1MAPTL3MBTL1 | |
| Furfural SCHEMBL10811266 | 0.79 | ALDH1A1 (1.00) | ALDH1A1POLBTDP1MAPTL3MBTL1 | |
| Furfural SCHEMBL626705 | 0.79 | ALDH1A1 (1.00) | ALDH1A1POLBTDP1MAPTL3MBTL1 | |
| Furfural SCHEMBL20439 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183020-B2 | Enzymatic oxidation of hydroxymethylfurfural | ARCHER DANIELS MIDLAND COMPANY (US) | 2012-05-22 | — | — | US | disclosed |
| US-20090053780-A1 | Enzymatic oxidation of HMF | ARCHER DANIELS MIDLAND CO. | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090053780-A1 | Enzymatic oxidation of HMF | AOX1, ADH1C, HPD | ALDH1A1 26/4885POLB 1087/4885TDP1 835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.