Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4223072 | 0.95 | HDAC1 (0.44) | HDAC1HDAC3HDAC2HDAC10HDAC11 | |
| SCHEMBL1496898 | 0.92 | HDAC3 (0.38) | HDAC1HDAC3HDAC2KMT2ADYRK1A | |
| SCHEMBL4229297 | 0.92 | HDAC1 (0.45) | HDAC1HDAC3HDAC2HDAC10HDAC11 | |
| SCHEMBL2383602 | 0.92 | MAPT (0.43) | HDAC1HDAC3HDAC2HDAC10HDAC11 | |
| SCHEMBL4234597 | 0.89 | MAPT (0.43) | HDAC1HDAC3HDAC2HDAC10HDAC11 | |
| SCHEMBL4229423 | 0.89 | MAPT (0.42) | HDAC1HDAC3HDAC2HDAC10HDAC11 | |
| SCHEMBL1497137 | 0.89 | HDAC3 (0.39) | HDAC1HDAC3HDAC2HDAC10HDAC11 | |
| SCHEMBL3223327 | 0.88 | SIGMAR1 (0.43) | KMT2ADYRK1AKDM4EHSD17B10 | |
| SCHEMBL2385692 | 0.85 | HDAC1 (0.45) | HDAC1HDAC3HDAC2HDAC10HDAC11 | |
| SCHEMBL1497209 | 0.84 | ALDH1A1 (0.41) | KMT2AKDM4EHSD17B10HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2133339-A1 | NOVEL (2-AMINOPHENYL)PYRIDINECARBOXAMIDE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-16 | — | — | EP | disclosed |