SCHEMBL4847237

SCHEMBL4847237

O=C(C(=O)c1cc(Br)cc(Br)c1)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CES2 O00748 13/20 0.64
CES1 P23141 12/20 0.64
ALOX15 P16050 1/20 0.48
HTT P42858 1/20 0.48
PARP1 P09874 1/20 0.47
KMT2A Q03164 1/20 0.46
RAB9A P51151 1/20 0.45
POLB P06746 1/20 0.44
MAPT P10636 1/20 0.44
DAO P14920 1/20 0.44
TSHR P16473 1/20 0.44
NAPRT Q6XQN6 1/20 0.44
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4204051 0.95 CES2 (0.64) CES2CES1ALOX15HTTPARP1
SCHEMBL31554264 0.85 CES2 (0.52) CES2CES1PARP1POLBTSHR
SCHEMBL31554270 0.85 CES2 (0.52) CES2CES1PARP1POLBTSHR
SCHEMBL4229652 0.84 CES2 (0.61) CES2CES1PARP1KMT2ARAB9A
SCHEMBL6142583 0.84 CES2 (0.45) CES2CES1ALOX15HTTKMT2A
SCHEMBL16503702 0.83 CES2 (0.82) CES2CES1PARP1RAB9APOLB
SCHEMBL39515 0.82 ALDH1A1 (0.64) ALOX15HTTPARP1KMT2ARAB9A
SCHEMBL649996 0.81 CES2 (0.80) CES2CES1KMT2ARAB9AMAPT
Benzil SCHEMBL29124640 0.80 CES2 (0.88) CES2CES1ALOX15PARP1KMT2A
Benzil SCHEMBL9517636 0.80 CES2 (1.00) CES2CES1ALOX15PARP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1493183-B1 PROCESS FOR MAKING AIR GAP CONTAINING SEMICONDUCTING DEVICES AND RESULTING SEMICONDUCTING DEVICE DOW GLOBAL TECHNOLOGIES LLC (US) 2012-12-05 EP disclosed
US-7381850-B2 Multifunctional unsymmetrically substituted monomers and polyarylene compositions therefrom DOW GLOBAL TECHNOLOGIES INC. (US) 2008-06-03 US disclosed
US-20060267000-A1 Multifunctional unsymmetrically substituted monomers and polyarylene compositions therefrom DOW GLOBAL TECHNOLOGIES INC. 2006-11-30 US disclosed
US-6946382-B2 Process for making air gap containing semiconducting devices and resulting semiconducting device DOW GLOBAL TECHNOLOGIES INC. (US) 2005-09-20 US disclosed
US-20050124172-A1 Process for making air gap containing semiconducting devices and resulting semiconducting device DOW GLOBAL TECHNOLOGIES LLC 2005-06-09 US disclosed
EP-1493183-A2 PROCESS FOR MAKING AIR GAP CONTAINING SEMICONDUCTING DEVICES AND RESULTING SEMICONDUCTING DEVICE DOW GLOBAL TECHNOLOGIES INC. (US) 2005-01-05 EP disclosed
WO-2004089862-A2 MULTIFUNCTIONAL UNSYMMETRICALLY SUBSTITUTED MONOMERS AND POLYARYLENE COMPOSITIONS THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2004-10-21 WO disclosed
WO-2003085719-A2 PROCESS FOR MAKING AIR GAP CONTAINING SEMICONDUCTING DEVICES AND RESULTING SEMICONDUCTING DEVICE DOW GLOBAL TECHNOLOGIES INC. (US) 2003-10-16 WO disclosed
WO-2001089527-A2 PHARMACEUTICAL COMPOSITION COMPRISING LORATADINE AND A NASAL DECONGESTANT SCHERING CORPORATION (US) 2001-11-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060267000-A1 Multifunctional unsymmetrically substituted monomers and polyarylene compositions therefrom WASF2, DDT, CAD CES2 1963/4885CES1 4150/4885ALOX15 207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.