Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | TUBB4A | P04350 | 9/20 | 0.55 |
| ▸ | TUBB | P07437 | 9/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 9/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 9/20 | 0.55 |
| ▸ | TUBA4A | P68366 | 9/20 | 0.55 |
| ▸ | TUBB4B | P68371 | 9/20 | 0.55 |
| ▸ | TUBB3 | Q13509 | 9/20 | 0.55 |
| ▸ | TUBB2A | Q13885 | 9/20 | 0.55 |
| ▸ | TUBB8 | Q3ZCM7 | 9/20 | 0.55 |
| ▸ | TUBA3E | Q6PEY2 | 9/20 | 0.55 |
| ▸ | TUBA1A | Q71U36 | 9/20 | 0.55 |
| ▸ | TUBA1C | Q9BQE3 | 9/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9187217 | 0.89 | NPC1 (0.58) | USP2MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL10151387 | 0.79 | SMN1; SMN2 (0.65) | MEN1KMT2ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL7199487 | 0.78 | CCND3 (0.69) | MAPTHTTPDE10ANPC1RAB9A | |
| SCHEMBL3966827 | 0.77 | CCND3 (0.67) | MEN1KMT2ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL250171 | 0.76 | CCND3 (0.70) | MEN1KMT2ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL15135554 | 0.76 | TUBB4A (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL15135615 | 0.76 | TUBB4A (0.61) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL426783 | 0.76 | PDGFRB (0.74) | USP2MEN1KMT2ASMN1; SMN2TUBB4A | |
| SCHEMBL29033613 | 0.75 | TUBB1 (0.43) | USP2ALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL24222544 | 0.75 | TUBB4A (0.57) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022121-A1 | INDOLES, DERIVATIVES AND ANALOGS THEREOF AND USES THEREFOR | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2012-01-26 | — | — | US | disclosed |
| US-20120022121-A1 | INDOLES, DERIVATIVES AND ANALOGS THEREOF AND USES THEREFOR | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2012-01-26 | — | — | US | disclosed |
| US-20120022121-A1 | INDOLES, DERIVATIVES AND ANALOGS THEREOF AND USES THEREFOR | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022121-A1 | INDOLES, DERIVATIVES AND ANALOGS THEREOF AND USES THEREFOR | TUBB, TUBB3, TUBB1 | USP2 3849/4885MEN1 1042/4885KMT2A 3095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.