Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL589892 | 0.81 | S1PR1 (0.37) | RARB | |
| SCHEMBL589158 | 0.77 | S1PR1 (0.40) | RARB | |
| SCHEMBL590675 | 0.75 | S1PR1 (0.48) | — | |
| SCHEMBL6684291 | 0.72 | RARB (0.48) | RARBMMP1MMP2MMP3MMP7 | |
| SCHEMBL10168087 | 0.71 | MMP1 (0.37) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL4186955 | 0.69 | RARB (0.56) | RARBMMP1MMP2MMP3MMP7 | |
| SCHEMBL8208555 | 0.69 | DGAT1 (0.54) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL11495636 | 0.69 | MMP1 (0.42) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL6687063 | 0.68 | ALOX5AP (0.43) | RARBMMP1MMP2MMP3MMP7 | |
| SCHEMBL222565 | 0.68 | RARB (0.61) | RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2017257-B1 | 2-AMINOBUTANOL COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | MITSUBISHI TANABE PHARMA CORP (JP) | 2014-08-06 | — | — | EP | disclosed |
| EP-2017257-A1 | 2-AMINOBUTANOL COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | Mitsubishi Tanabe Pharma Corporation (JP) | 2009-01-21 | — | — | EP | disclosed |