SCHEMBL423456

SCHEMBL423456

OCCNc1ccc(Cc2ccc(NCCO)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.43
ADRA2B P18089 1/20 0.43
ADRA2C P18825 1/20 0.43
MAPT P10636 3/20 0.41
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
RORC P51449 1/20 0.39
LMNA P02545 3/20 0.39
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 2/20 0.39
HPGD P15428 2/20 0.39
HTT P42858 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
POLB P06746 3/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
MAPK1 P28482 2/20 0.38
KCNH3 Q9ULD8 1/20 0.38
RECQL P46063 1/20 0.37
MCL1 Q07820 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6152657 0.87 MAPT (0.50) MAPTLMNAALDH1A1KDM4EPOLB
SCHEMBL11507189 0.85 MAPT (0.55) MAPTLMNAALDH1A1KDM4EPOLB
SCHEMBL2759019 0.84 ALDH1A1 (0.47) ADRA2AADRA2BADRA2CMAPTRORC
SCHEMBL10676866 0.82 ALDH1A1 (0.55) MAPTRORCLMNAALDH1A1HPGD
SCHEMBL8276466 0.82 LOXL2 (0.44) MAPTRORC
SCHEMBL9551618 0.81 MAPT (0.46) ADRA2AADRA2BADRA2CMAPTLMNA
SCHEMBL11035193 0.80 MAPT (0.44) MAPTALDH1A1KDM4ESMN1; SMN2MAPK1
SCHEMBL11015521 0.80 MAPT (0.44) MAPTLMNAALDH1A1KDM4EPOLB
SCHEMBL15278104 0.80 ESR1 (0.43) ADRA2AADRA2BADRA2CMAPTESR1
SCHEMBL9771418 0.79 TAAR1 (0.48) ADRA2AALDH1A1KDM4ESMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190233639-A1 POLYALKYLENE TEREPHTHALATE COMPOSITIONS LANXESS DEUTSCHLAND GMBH (DE) 2019-08-01 US claimed
EP-3510102-A1 POLYALKYLENE TEREPHTHALATE COMPOSITIONS Lanxess Deutschland GmbH (DE) 2019-07-17 EP claimed
WO-2018046244-A1 POLYALKYLENE TEREPHTHALATE COMPOSITIONS LANXESS DEUTSCHLAND GMBH (DE) 2018-03-15 WO claimed
EP-3290476-A1 POLYALKYLENE TEREPHTHALATE COMPOSITIONS LANXESS Deutschland GmbH (DE) 2018-03-07 EP claimed
EP-1017701-B1 CYCLOPENTAPHENANTHRENYL TITANIUM COMPLEXES AND POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC (US) 2003-03-19 EP claimed
US-4179577-A Polymerisable esters derived from a phenolic unsaturated ketone CIBA-GEIGY CORPORATION (US) 1979-12-18 US claimed
EP-3820926-B1 RADIATION CURABLE COMPOSITION ALLNEX Belgium SA (BE) 2024-05-15 EP disclosed
US-11981771-B2 Radiation curable composition ALLNEX BELGIUM S.A. (BE) 2024-05-14 US disclosed
US-11926727-B2 Epoxy resin composition HUNTSMAN INTERNATIONAL LLC (US) 2024-03-12 US disclosed
EP-4298145-A1 ONE COMPONENT POLYMERIZABLE COMPOSITION FOR TRICKLE IMPREGNATION Huntsman Advanced Materials Licensing (Switzerland) GmbH (CH) 2024-01-03 EP disclosed
EP-3864063-B1 A PROCESS FOR PREPARING A PREPREG BINDER COMPOSITION, A PREPREG AND USE THEREOF BASF SE (DE) 2023-11-29 EP disclosed
US-20230312987-A1 Method, kit and composition for non-destructive in situ repair or relining of deteriorated pipelines with a dual use system APPLIED RESIN S.L. (ES) 2023-10-05 US disclosed
EP-4253819-A1 METHOD, KIT AND COMPOSITION FOR NON-DESTRUCTIVE IN SITU REPAIR (RELINING) OF DETERIORATED PIPELINES WITH A DUAL USE SYSTEM Applied Resin S.L. (ES) 2023-10-04 EP disclosed
US-4175173-A Powder coating compositions containing an epoxide resin and an acid hardener CIBA-GEIGY CORPORATION (US) 1979-11-20 US disclosed
US-4130511-A AROMATIC COMPOUND, INORGANIC NITRATE CIBA-GEIGY CORPORATION (US) 1978-12-19 US disclosed
US-4125557-A Hydrosulfite-bleachable ketonimine dyes for paper AMERICAN CYANAMID COMPANY (US) 1978-11-14 US disclosed
US-4124760-A Photopolymerizable diepoxides containing a nitrogen heterocycle CIBA-GEIGY CORPORATION (US) 1978-11-07 US disclosed
US-4115296-A Polyhalocarboxylic acid salts as accelerators for curing epoxide resins CIBA-GEIGY CORPORATION (US) 1978-09-19 US disclosed
US-4111907-A PHOTOPOLYMERIZABLE KETONES CIBA-GEIGY CORPORATION (US) 1978-09-05 US disclosed
US-4069204-A HEAT AND MOISTURE RESISTANCE AMERICAN CYANAMID COMPANY (US) 1978-01-17 US disclosed