Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 9/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4235315 | 0.81 | PDE4A (0.31) | — | |
| SCHEMBL4243417 | 0.76 | FABP4 (0.33) | HTR6ACVR1MEN1KMT2ABRD4 | |
| SCHEMBL4243414 | 0.75 | PSEN1 (0.37) | HTR6ACVR1KMT2ABRD4 | |
| SCHEMBL4062215 | 0.71 | KDR (0.34) | MAPT | |
| SCHEMBL4053970 | 0.69 | KDM4E (0.31) | — | |
| SCHEMBL4235902 | 0.68 | HTR6 (0.41) | HTR6MEN1KMT2ABRD4 | |
| SCHEMBL4233727 | 0.66 | KDR (0.30) | — | |
| SCHEMBL4233489 | 0.65 | KDM4E (0.48) | HTR6MEN1KMT2ABRD4 | |
| SCHEMBL4225953 | 0.65 | HTR6 (0.35) | HTR6MEN1KMT2ABRD4 | |
| SCHEMBL4234116 | 0.64 | HTR6 (0.45) | HTR6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009115874-A2 | NOVEL HETEROCYCLIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | MATRIX LABORATORIES LTD. (IN) | 2009-09-24 | — | — | WO | disclosed |