Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.51 |
| ▸ | HTR1A | P08908 | 6/20 | 0.51 |
| ▸ | HTR2A | P28223 | 5/20 | 0.51 |
| ▸ | DRD3 | P35462 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12403727 | 0.79 | HRH3 (0.62) | DRD2HTR1AHTR2ADRD3LMNA | |
| SCHEMBL1114667 | 0.78 | HRH3 (0.59) | DRD2HTR1AHTR2ADRD3LMNA | |
| SCHEMBL1780938 | 0.77 | DRD2 (0.57) | DRD2HTR1AHTR2ADRD3LMNA | |
| SCHEMBL1114455 | 0.74 | DRD2 (0.51) | DRD2HTR1AHTR2ADRD3LMNA | |
| SCHEMBL1114606 | 0.74 | DRD2 (0.55) | DRD2HTR1AHTR2ADRD3LMNA | |
| SCHEMBL22417421 | 0.73 | HRH3 (0.56) | DRD2HTR1AHTR2ADRD3LMNA | |
| SCHEMBL2002856 | 0.72 | DRD2 (0.55) | DRD2HTR1AHTR2ALMNAKDM4E | |
| SCHEMBL12403746 | 0.72 | DRD2 (0.66) | DRD2HTR1AHTR2ADRD3MAPT | |
| SCHEMBL1114549 | 0.72 | DRD2 (0.52) | DRD2HTR1AHTR2ADRD3LMNA | |
| SCHEMBL1114150 | 0.71 | DRD2 (0.64) | DRD2HTR1AHTR2ADRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009145590-A2 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AND USE THEREOF | SK HOLDINGS CO., LTD. (KR) | 2009-12-03 | — | — | WO | claimed |