SCHEMBL1114455

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1114442	0.88	LMNA (0.64)	DRD2DRD3DRD4SLC6A2SLC6A4
	SCHEMBL1780938	0.83	DRD2 (0.57)	DRD2DRD3DRD4SLC6A2SLC6A4
	SCHEMBL1114606	0.82	DRD2 (0.55)	DRD2DRD3DRD4SLC6A2SLC6A4
	SCHEMBL1114549	0.82	DRD2 (0.52)	DRD2DRD3DRD4SLC6A2SLC6A4
	SCHEMBL12403727	0.81	HRH3 (0.62)	DRD2DRD3DRD4SLC6A2SLC6A4
	SCHEMBL1114138	0.81	DRD2 (0.49)	DRD2DRD3SLC6A2SLC6A4HTR1A
	SCHEMBL27825969	0.81	KCNH2 (0.57)	DRD2DRD3DRD4HTR1AHTR2A
	SCHEMBL1114925	0.80	LMNA (0.63)	DRD2DRD3DRD4SLC6A2SLC6A4
	SCHEMBL1114848	0.78	HTR1A (0.66)	DRD2DRD3DRD4SLC6A2SLC6A4
	Hydrochloric Acid SCHEMBL1114721	0.78	HTR1A (0.65)	DRD2DRD3DRD4SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.