SCHEMBL1114667

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1114150	0.92	DRD2 (0.64)	DRD2HTR1AHTR2ADRD3
	SCHEMBL12403673	0.87	LMNA (0.72)	LMNAKDM4EDRD2HTR1AHTR2A
	SCHEMBL2002856	0.87	DRD2 (0.55)	HRH3LMNAKDM4EDRD2HTR1A
	Hydrochloric Acid SCHEMBL1114457	0.86	LMNA (0.74)	LMNAKDM4EDRD2HTR1AHTR2A
	SCHEMBL12403727	0.85	HRH3 (0.62)	HRH3LMNAKDM4EDRD2HTR1A
	SCHEMBL2001553	0.83	DRD2 (0.57)	DRD2HTR1AHTR2AALDH1A1
	SCHEMBL1780938	0.81	DRD2 (0.57)	LMNAKDM4EDRD2HTR1AHTR2A
	SCHEMBL2004136	0.80	DRD2 (0.65)	DRD2HTR1AHTR2A
	SCHEMBL22417421	0.79	HRH3 (0.56)	HRH3LMNAKDM4EDRD2HTR1A
	SCHEMBL4235263	0.78	DRD2 (0.51)	LMNAKDM4EDRD2HTR1AHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.