Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22386773 | 0.84 | LTA4H (0.59) | HRH1HRH3SIGMAR1KCNH2LTA4H | |
| SCHEMBL2741684 | 0.84 | LTA4H (0.59) | HRH1HRH3SIGMAR1KCNH2LTA4H | |
| Hydrochloric Acid SCHEMBL227403 | 0.83 | LTA4H (0.58) | HRH1HRH3SIGMAR1KCNH2LTA4H | |
| Hydrochloric Acid SCHEMBL6596661 | 0.81 | LTA4H (0.59) | HRH1HRH3SIGMAR1KCNH2LTA4H | |
| SCHEMBL4767153 | 0.81 | SIGMAR1 (0.63) | HRH1HRH3SIGMAR1KCNH2KDM4E | |
| SCHEMBL4228627 | 0.80 | ALDH1A1 (0.45) | HRH1HRH3SIGMAR1KCNH2ACHE | |
| SCHEMBL4229105 | 0.79 | ADRA2A (0.48) | HRH3KDM4EBCHEACHE | |
| SCHEMBL2741683 | 0.78 | HRH3 (0.62) | HRH3SIGMAR1KCNH2 | |
| SCHEMBL7031548 | 0.78 | HRH3 (0.62) | HRH3SIGMAR1KCNH2 | |
| Hydrochloric Acid SCHEMBL223935 | 0.77 | HRH3 (0.61) | HRH3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | NPY1R, NPY5R, NPY2R | HRH1 217/4885HRH3 210/4885SIGMAR1 303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.