SCHEMBL4235763

SCHEMBL4235763

N#CC=CC(=O)N(c1ccccc1)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TRPM8 Q7Z2W7 6/20 0.58
▸ NPSR1 Q6W5P4 2/20 0.47
▸ ALDH1A1 P00352 5/20 0.40
▸ KMT2A Q03164 3/20 0.40
▸ NPC1 O15118 1/20 0.40
▸ POLB P06746 1/20 0.40
▸ HTT P42858 1/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ ATM Q13315 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ MCL1 Q07820 1/20 0.36
▸ MEN1 O00255 2/20 0.35
▸ SNCA P37840 1/20 0.35
▸ MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20314815 0.78 TRPM8 (0.43) TRPM8ALDH1A1KMT2ANPC1MEN1
SCHEMBL30764040 0.76 TRPM8 (0.66) TRPM8NPSR1ALDH1A1KMT2ANPC1
SCHEMBL7567512 0.73 TRPM8 (0.61) TRPM8NPSR1ALDH1A1KMT2ANPC1
SCHEMBL30532219 0.73 TRPM8 (1.00) TRPM8NPSR1ALDH1A1NPC1TDP1
SCHEMBL4157271 0.73 TRPM8 (0.61) TRPM8NPSR1ALDH1A1KMT2ANPC1
SCHEMBL10271031 0.73 TRPM8 (1.00) TRPM8NPSR1ALDH1A1NPC1TDP1
SCHEMBL8006032 0.71 TRPM8 (0.59) TRPM8NPSR1ALDH1A1KMT2ANPC1
SCHEMBL11795206 0.70 TRPM8 (0.53) TRPM8NPSR1ALDH1A1KMT2ANPC1
SCHEMBL11862805 0.70 NPSR1 (0.56) TRPM8NPSR1ALDH1A1KMT2ANPC1
SCHEMBL1629579 0.70 TRPM8 (0.57) TRPM8NPSR1ALDH1A1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6291586-B2 Polymeric films that contain a polymeric matrix and the absorbing material are used as the top layer of multilayer retroreflective sheetings and conformable marking sheets; resists blooming and migration 3M INNOVATIVE PROPERTIES COMPANY 2001-09-18 — — US claimed
US-20010007885-A1 AMIDE FUNCTIONAL ULTRAVIOLET LIGHT ABSORBERS FOR POLYURETHANES AND POLYUREAS MINNESOTA MINING AND MANUFACTURING COMPANY 2001-07-12 — — US claimed
US-6150440-A A POLYMERIC FILM COMPRISING A POLYOLEFIN MODIFIED BY HYDROGEN-BONDING WITH AN AMIDE FUNCTIONAL ULTRAVIOLET LIGHT ABSORBING COMPOUND 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-11-21 — — US claimed
CN-110256289-B Preparation method of ultraviolet absorbent UV-3030 威海金威化学工业有限责任公司 2022-04-22 — — CN disclosed
WO-2009101016-A2 MODIFIED HYBRID NANOPARTICLES BASF SE (DE) 2009-08-20 — — WO disclosed
US-6291586-B2 Polymeric films that contain a polymeric matrix and the absorbing material are used as the top layer of multilayer retroreflective sheetings and conformable marking sheets; resists blooming and migration 3M INNOVATIVE PROPERTIES COMPANY 2001-09-18 — — US disclosed
US-20010007885-A1 AMIDE FUNCTIONAL ULTRAVIOLET LIGHT ABSORBERS FOR POLYURETHANES AND POLYUREAS MINNESOTA MINING AND MANUFACTURING COMPANY 2001-07-12 — — US disclosed
US-6150440-A A POLYMERIC FILM COMPRISING A POLYOLEFIN MODIFIED BY HYDROGEN-BONDING WITH AN AMIDE FUNCTIONAL ULTRAVIOLET LIGHT ABSORBING COMPOUND 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-11-21 — — US disclosed
EP-1025157-A1 AMIDE FUNCTIONAL ULTRAVIOLET LIGHT ABSORBERS FOR POLYURETHANES AND POLYUREAS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-08-09 — — EP disclosed
US-5994431-A Amide functional ultraviolet light absorbers for polyolefins 3M INNOVATIVE PROPERTIES COMPANY (US) 1999-11-30 — — US disclosed
WO-1999023151-A1 AMIDE FUNCTIONAL ULTRAVIOLET LIGHT ABSORBERS FOR POLYURETHANES AND POLYUREAS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-05-14 — — WO disclosed
EP-0896605-A1 AMIDE FUNCTIONAL ULTRAVIOLET LIGHT ABSORBERS FOR POLYOLEFINS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-02-17 — — EP disclosed
WO-1997042261-A1 AMIDE FUNCTIONAL ULTRAVIOLET LIGHT ABSORBERS FOR POLYOLEFINS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-11-13 — — WO disclosed
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