Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3339534 | 1.00 | LMNA (0.33) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL13303100 | 1.00 | LMNA (0.33) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL3341898 | 0.89 | — | — | |
| SCHEMBL13303090 | 0.77 | MAPT (0.35) | — | |
| SCHEMBL3339446 | 0.74 | — | — | |
| SCHEMBL3333118 | 0.74 | — | — | |
| SCHEMBL920166 | 0.67 | TSHR (0.42) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL465348 | 0.67 | TSHR (0.42) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL7155455 | 0.67 | TSHR (0.42) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL37134 | 0.67 | TSHR (0.42) | LMNAALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090320718-A1 | FLUOROSURFACTANTS | MERCK PATENT GESELLSCHAFT (DE) | 2009-12-31 | — | — | US | disclosed |
| EP-2035132-A2 | FLUOROSURFACTANTS | MERCK PATENT GmbH (DE) | 2009-03-18 | — | — | EP | disclosed |
| WO-2008003447-A2 | FLUOROSURFACTANTS | MERCK PATENT GMBH (DE) | 2008-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090320718-A1 | FLUOROSURFACTANTS | FPR3, Q6ZSR9, SGMS2 | LMNA 1609/4885ALDH1A1 4113/4885HSD17B10 2531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.