SCHEMBL7155455

SCHEMBL7155455

OCCCCCCCCCCCCN(CCCCCCCCCCCCO)CCCCCCCCCCCCO

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
ALDH1A1 P00352 3/20 0.42
LMNA P02545 2/20 0.42
HSD17B10 Q99714 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.37
GPR84 Q9NQS5 1/20 0.36
FFAR1 O14842 1/20 0.36
FFAR4 Q5NUL3 1/20 0.36
MIF P14174 1/20 0.32
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920166 1.00 TSHR (0.42) TSHRALDH1A1LMNAHSD17B10MEN1
SCHEMBL465348 1.00 TSHR (0.42) TSHRALDH1A1LMNAHSD17B10MEN1
SCHEMBL37134 1.00 TSHR (0.42) TSHRALDH1A1LMNAHSD17B10MEN1
SCHEMBL16105079 0.97 TSHR (0.40) TSHRALDH1A1LMNAHSD17B10MEN1
SCHEMBL62158 0.96 TSHR (0.41) TSHRALDH1A1LMNAHSD17B10MEN1
SCHEMBL10820949 0.94 LMNA (0.38) TSHRALDH1A1LMNAHSD17B10MEN1
SCHEMBL6072706 0.94 LMNA (0.38) TSHRALDH1A1LMNAHSD17B10MEN1
SCHEMBL14412047 0.94 LMNA (0.38) TSHRALDH1A1LMNAHSD17B10MEN1
SCHEMBL6072533 0.94 LMNA (0.38) TSHRALDH1A1LMNAHSD17B10MEN1
SCHEMBL2784048 0.93 TSHR (0.39) TSHRALDH1A1LMNAHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117534810-A Full-degradable antibacterial slow-release nutrition bionic sponge and preparation method and application thereof 陕西科技大学 2024-02-09 CN disclosed
US-6541663-B2 As oxidation catalyst for amine-group-containing primary amines to carboxylic acids SYNGENTA PARTICIPATIONS AG (CH) 2003-04-01 US disclosed
US-20020099246-A1 Process for preparation of aminocarboxylic acids SYNGENTA PARTICIPATIONS AG (CH) 2002-07-25 US disclosed
US-20020038050-A1 Process for the manufacture of amino carboxylic acids SIEBENHAAR BERND (DE) 2002-03-28 US disclosed
EP-1144359-A1 PREPARATION OF AMINOCARBOXYLIC ACIDS BY OXIDATION OF PRIMARY AMINO-ALCOHOLS Syngenta Participations AG (CH) 2001-10-17 EP disclosed
EP-1140356-A1 PROCESS FOR PREPARATION OF AMINOCARBOXYLIC ACIDS Novartis AG (CH) 2001-10-10 EP disclosed
WO-2000043351-A1 PREPARATION OF AMINOCARBOXYLIC ACIDS BY OXIDATION OF PRIMARY AMINO-ALCOHOLS SYNGENTA PARTICIPATIONS AG (CH) 2000-07-27 WO disclosed
WO-2000032310-A1 PROCESS FOR PREPARATION OF AMINOCARBOXYLIC ACIDS SYNGENTA PARTICIPATIONS AG (CH) 2000-06-08 WO disclosed
EP-0482583-A2 Deinking agent for regeneration of waste paper DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 1992-04-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020099246-A1 Process for preparation of aminocarboxylic acids AOC3, CDY1; CDY1B, AOC2 TSHR 3357/4885ALDH1A1 2393/4885LMNA 769/4885
US-20020038050-A1 Process for the manufacture of amino carboxylic acids ADH1A, ADH1C, AOC3 TSHR 1162/4885ALDH1A1 20/4885LMNA 3655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.