Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 15/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 15/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.42 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12115560 | 0.89 | PSEN1 (0.42) | L3MBTL1KEAP1NFE2L2PPARG | |
| SCHEMBL1317802 | 0.80 | KEAP1 (0.43) | L3MBTL1KEAP1NFE2L2 | |
| SCHEMBL4237417 | 0.79 | KEAP1 (0.46) | L3MBTL1KEAP1NFE2L2DAGLA | |
| SCHEMBL1110293 | 0.78 | PSEN1 (0.38) | KEAP1NFE2L2PPARGDAGLBDAGLA | |
| SCHEMBL4239508 | 0.78 | KEAP1 (0.44) | L3MBTL1KEAP1NFE2L2 | |
| SCHEMBL1319761 | 0.78 | KEAP1 (0.43) | L3MBTL1KEAP1NFE2L2 | |
| SCHEMBL1110442 | 0.77 | RORC (0.45) | KEAP1NFE2L2 | |
| SCHEMBL4236968 | 0.76 | KEAP1 (0.40) | L3MBTL1KEAP1NFE2L2 | |
| SCHEMBL1319419 | 0.76 | KEAP1 (0.43) | L3MBTL1KEAP1NFE2L2 | |
| SCHEMBL4236945 | 0.76 | KEAP1 (0.46) | L3MBTL1KEAP1NFE2L2DAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009127723-A1 | NEW ARYLSULPHONYLGLYCINE DERIVATIVES, THE PREPARATION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-10-22 | — | — | WO | disclosed |