Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | NOS1 | P29475 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329851 | 0.81 | TSHR (0.57) | CYP2C19CYP1A2TSHRLOXL2ALDH1A1 | |
| SCHEMBL43494 | 0.79 | CYP2C19 (0.57) | CYP2C19CYP1A2TSHRLOXL2ALDH1A1 | |
| SCHEMBL10815212 | 0.79 | CYP2C19 (0.57) | CYP2C19CYP1A2TSHRLOXL2ALDH1A1 | |
| SCHEMBL4833795 | 0.79 | ALDH1A1 (0.61) | CYP2C19CYP1A2TSHRLOXL2ALDH1A1 | |
| SCHEMBL12402233 | 0.79 | ALDH1A1 (0.61) | CYP2C19CYP1A2TSHRLOXL2ALDH1A1 | |
| SCHEMBL1827672 | 0.79 | ALDH1A1 (0.61) | CYP2C19CYP1A2TSHRLOXL2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11879770 | 0.77 | ALDH1A1 (0.60) | CYP2C19CYP1A2LOXL2ALDH1A1MAPT | |
| Ethylene SCHEMBL11190134 | 0.76 | CYP2C19 (0.54) | CYP2C19CYP1A2TSHRLOXL2ALDH1A1 | |
| SCHEMBL10916926 | 0.76 | CYP2C19 (0.58) | CYP2C19CYP1A2TSHRLOXL2ALDH1A1 | |
| SCHEMBL10916929 | 0.76 | CYP2C19 (0.58) | CYP2C19CYP1A2TSHRLOXL2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007501701-A | — | — | 2007-02-01 | — | — | JP | claimed |
| EP-1660232-A1 | HYDROTREATING AND/OR HYDROCRACKING CATALYST OF HYDROCARBONS AND PREPARATION THEREOF | Total France (FR) | 2006-05-31 | — | — | EP | claimed |
| WO-2005016518-A1 | HYDROTREATING AND/OR HYDROCRACKING CATALYST OF HYDROCARBONS AND PREPARATION THEREOF | TOTAL FRANCE (FR) | 2005-02-24 | — | — | WO | claimed |
| EP-1660232-B1 | HYDROTREATING AND/OR HYDROCRACKING CATALYST OF HYDROCARBONS AND PREPARATION THEREOF | TOTAL RAFFINAGE MARKETING (FR) | 2009-07-22 | — | — | EP | disclosed |
| EP-1660232-A1 | HYDROTREATING AND/OR HYDROCRACKING CATALYST OF HYDROCARBONS AND PREPARATION THEREOF | Total France (FR) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005016518-A1 | HYDROTREATING AND/OR HYDROCRACKING CATALYST OF HYDROCARBONS AND PREPARATION THEREOF | TOTAL FRANCE (FR) | 2005-02-24 | — | — | WO | disclosed |