Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12402233 | 1.00 | ALDH1A1 (0.61) | ALDH1A1MAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL4833795 | 1.00 | ALDH1A1 (0.61) | ALDH1A1MAPTKMT2AMEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL11879770 | 0.98 | ALDH1A1 (0.60) | ALDH1A1MAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL1817934 | 0.80 | TSHR (0.54) | ALDH1A1MAPTCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL1817933 | 0.80 | TSHR (0.54) | ALDH1A1MAPTCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL2673969 | 0.79 | LOXL2 (0.59) | ALDH1A1MAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL10916926 | 0.79 | CYP2C19 (0.58) | ALDH1A1MAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL10916929 | 0.79 | CYP2C19 (0.58) | ALDH1A1MAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL4237740 | 0.79 | CYP2C19 (0.61) | ALDH1A1MAPTKMT2AMEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL10915423 | 0.78 | CYP2C19 (0.56) | ALDH1A1MAPTKMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | US | disclosed |
| EP-2318374-A2 | INSECTICIDAL BENZENEDICARBOXAMIDE DERIVATIVE | Bayer CropScience AG (DE) | 2011-05-11 | — | — | EP | disclosed |
| US-20100056507-A1 | PHENYL DERIVATIVES AND THEIR USE AS A MEDICAMENT | IPSEN PHARMA S.A.S. (FR) | 2010-03-04 | — | — | US | disclosed |
| WO-2010012442-A2 | INSECTICIDAL BENZENEDICARBOXAMIDE DERIVATIVE | BAYER CROPSCIENCE AG (DE) | 2010-02-04 | — | — | WO | disclosed |
| US-20080287438-A1 | Agent for preventing or treating neuropathy | MOMOSE YU | 2008-11-20 | — | — | US | disclosed |
| US-7423159-B2 | Agent for preventing or treating neuropathy | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-09 | — | — | US | disclosed |
| EP-1339710-B1 | 3-OXADIAZOL-5-YL-1-AMINOALKYL-1H-INDOLE DERIVATIVES | AMRAD OPERATIONS PTY LTD (AU) | 2006-03-01 | — | — | EP | disclosed |
| US-20060004069-A1 | Agent for preventing or treating neuropathy | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-05 | — | — | US | disclosed |
| US-6930118-B2 | 3-Oxadiazol-5-yl-1-aminoalkyl-1h-indole derivatives | AMRAD OPERATIONS PTY. LTD. (AU) | 2005-08-16 | — | — | US | disclosed |
| EP-1339710-A4 | 3-OXADIAZOL-5-YL-1-AMINOALKYL-1H-INDOLE DERIVATIVES | AMRAD OPERATIONS PTY LTD (AU) | 2004-05-12 | — | — | EP | disclosed |
| US-20040034073-A1 | 3-Oxadiazol-5-yl-1-aminoalkyl-1h-indole derivatives | AMRAD OPERATIONS PTY. LTD. (AU) | 2004-02-19 | — | — | US | disclosed |
| EP-1339710-A1 | 3-OXADIAZOL-5-YL-1-AMINOALKYL-1H-INDOLE DERIVATIVES | Amrad Operations Pty.,Ltd. (AU) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002036590-A1 | 3-OXADIAZOL-5-YL-1-AMINOALKYL-1H-INDOLE DERIVATIVES | AMRAD OPERATIONS PTY LTD (AU) | 2002-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034073-A1 | 3-Oxadiazol-5-yl-1-aminoalkyl-1h-indole derivatives | CNR1, CNR2, OPRK1 | ALDH1A1 497/4885MAPT 3955/4885KMT2A 2930/4885 |
| US-20060004069-A1 | Agent for preventing or treating neuropathy | NR2C2, NR0B2, NR2E1 | ALDH1A1 2652/4885MAPT 3203/4885KMT2A 1653/4885 |
| US-20080287438-A1 | Agent for preventing or treating neuropathy | NR2C2, NR0B2, NR2E1 | ALDH1A1 2652/4885MAPT 3203/4885KMT2A 1653/4885 |
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | DDT, BRD9, BCL2A1 | ALDH1A1 928/4885MAPT 4079/4885KMT2A 657/4885 |
| US-20100056507-A1 | PHENYL DERIVATIVES AND THEIR USE AS A MEDICAMENT | CNR2, CNR1, TRPV1 | ALDH1A1 2439/4885MAPT 1118/4885KMT2A 2065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.